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Different Scenarios

Contents of this bit:

Cardiac/Respiratory Arrest (A Code)
Cardiac (Hemodynamically) Unstable
Increased Intracranial Pressure (ICP)
Apparent Difficult Airway - Anatomy, Injury, Physical/Mechanical Problems
Known Difficult Airway
Unstable Cervical Spine
Combative Patient


There are numerous scenarios which may be encountered when attending an emergency intubation on the ward or ICU. This is a description of the most common situations that are faced and the techiques which may be appropriate for each situation. In each sceanrio you can click on one of the available options and be taken to a description of that technique.

Remember there may be more than one potential problem with conflicting solutions. A judgement may need to be made as to which concern is paramount and cosideration may have to be given to altering the procedure in view of the patients overall condition.

Pre-oxygenate before attempting any airway maneuvers. The techniques of jaw thrust, chin lift, head tilt and mask ventilation/assistance should be performed to help temporize the situation. And, if the airway reflexes are taken away, cricoid pressure can be performed to guard against aspiration.
Preoxygenation


Cardiac/Respiratory Arrest (A Code)


The patient is not awake, often has no blood pressure or pulse and is not ventilating. The physician's job is to place the endotracheal tube as quickly as possible; interrupting the code for the shortest time possible. Understanding that obtaining an airway is paramount to a successful code. Follow the ACLS Algorithm for each specific situation.

Techniques:

Direct laryngoscopy without any pharmacologic aids.

The primary concern is to establish oxygenation, this initially means ventilation with 100% oxygen by bag and mask. In this situation, the patient is not responsive, therefore, there is no reason to use any pharmacologic adjuvants to intubation and since the patient is not oxygenating and ventilating it is imperative that the airway be secured as quickly as possible. Whether the airway appears difficult or not it direct laryngoscopy can be attempted, since this can be done quickly. This is accomplished by preparing to intubate and than stopping CPR for the shortest time possible, securing the airway and then allowing CPR to resume once you have confirmed tube placement. If intubation proves difficult then stop and resume ventilation by mask. Do not allow the patient to become hypoxic during protracted attempts to intubate.


Cardiac (Hemodynamically) Unstable


This patient is hemodynamically compromised. You must determine the most stable way to intubate a person in this situation. Using the inappropriate medication may significantly compromise the patient.

Techniques:

Awake and topicalize
Sedate and topicalize
Fiberoptic
Rapid Sequence Intubation

Factors to be taken into consideration[reference 1]:
Degree of hemodynamic compromise.
Level of consciousness.
Airway evaluation.

Hemodynamic status:

1. Systolic BP less than 80 mmHg
No induction agent should be used, however, if a muscle relaxant is to be used, an amnestic can be given for patient comfort.
Scopolamine 0.5 mg or midazolam 1-2 mg, are good amnestics and fentanyl 0.5-1.0 ug/kg is a good analgesic.
2. Systolic BP 80-100 mmHg
Small doses of thiopental 0.3-1.0 mg/kg or etomidate 0.1-0.2mg/kg both titrated to effect. Succinylcholine 1.5 mg/kg, unless contraindicated.
3. Systolic BP greater than 100 mmHg
Thiopental 2-5mg/kg or etomidate 0.2-0.3 mg/kg, both titrated to effect, are effective induction agents, though etomidate is the more hemodynamically stable of the two and would be the better choice.[reference 2]

If the airway appears normal, rapid sequence intubation would be an acceptable intubation technique. The least cardiac depressant induction agent is etomidate and is the best option in this situation [reference 2]. Etomidate may still cause cardiac depression and hypotension.

If the airway did not appear normal or gave the appearance of a difficult intubation, inducing anesthesia is no longer an option. If there are no contraindications, sedation and topicalization would be the next option. Midazolam can be used for amnesia. Fentanyl can be used for analgesia. If both midazolam and fentanyl are used, remember that they have synergistic effects on cardiac and respiratory depression.


Increased Intracranial Pressure (ICP)


During intubation of a patient with increased ICP, any additional increases in ICP must be avoided, adequate mean arterial pressure (MAP) is required to maintain adequate cerebral perfusion pressure (CPP). The re is a dilemma between reducing ICP and maintaining CPP

Techniques:

Awake and topicalize
Sedate and topicalize
Rapid sequence intubation

Topicalization may make it difficult to adequately blunt reflexes, and coughing and bucking may occur causing considerable increases in ICP with potentially devastating results. Sedation may help, however, this can cause with hypoventilation and hypercapnia with a subsequent increase in cerebral blood flow. With the increase in blood flow there is an increase in cerebral blood volume and in a patient who has exhausted their compensatory mechanisms this leads to an increase in ICP.

Rapid sequence intubation with etomidate and succinycholine would be the best choice if the airway evaluation is reasonable. Except for ketamine, all IV induction agents decrease ICP [reference 3]. However, the dose required to decrease ICP often produces a large decrease in MAP, this can lead to a considerable decrease in CPP. and cerebral ischemia

Etomidate would be the induction agent of choice in this situation, titrated to effect it can blunt the response to laryngoscopy and intubation, but still maintain adequate CPP. Succinylcholine's effect on ICP is controversial. There are some indications that ICP is increased with succinylcholine use, however, this effect is minimal and transient and can be attenuated with mild hyperventilation. Also, there has been work that shows succinylcholine has no effect on ICP [reference 4]. The benefit gained from rapid control of the airway, especially when there is risk of regurgitation, may outway the risk of any small increases in ICP attributable to succinylcholine. Rapid intubation also allows earlier institution of hyperventilation for ICP control.

Lidocaine, IV and topical, has been shown to blunt reflexes from airway stimulation and thus control ICP [reference 5]. However, since topical lidocaine is difficult to use in this situation, IV lidocaine [reference 6} can be used to attenuate the airway reflexes and can reduce the ICP response to endotracheal suctioning for up to 15 minutes.


Burns/Crush Injury/Spinal Cord Injury


In these types of injuries succinylcholine may be contraindicated [reference 7] due the possibility of massive potassium release.

Techniques:

Awake and Topicalize
Sedate and Topicalize
Rapid Sequence Intubation

All the non-depolarizing neuro-muscular blocking agents (NMBs) have a longer onset time than succinylcholine. If higher doses of a nondepolaizing NMB is given to shorten the onset of action then the duration of action is prolonged and cardiovascular side effect or histamine release may occur (eg atracurium). It has been said that NMBs have no place outside the OR. If a muscle relaxant is given and intubation proves impossible, then the option of allowing the patient to wake-up and breath spontaneously has been removed. The airway may be lost and a surgical airway may need to be obtained.
Rocuronium may the best alternative when succinylcholine is contraindicated. It appears to have the most rapid onset of all the nondepolarizing NMBs.


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