Bio

My primary research interest is harnessing adaptive interventions to transform health care. Adaptive interventions address the changing needs of individuals by modifying their treatment based on dynamic information about their state and progress. An important focus of my work is the Just-In-Time Adaptive Intervention (JITAI), a special type of adaptive intervention that leverages powerful mobile and sensing technologies to adapt the delivery of support in real-world settings—in near real-time, as well as interventions that blend human-delivered (e.g., coaching session) components with digital (e.g., mobile-based) components, which necessitates adaptation on multiple timescales. This work is highly multidisciplinary, spanning behavioral health and applied psychology, while also being tightly integrated with advanced research methodology

Inbal Billie Nahum-Shani

Selected Publications

  • Nahum-Shani, I., & Murphy, S. A. (2025). Just-in-time adaptive interventions: Where are we now and what is next? Annual Review of Psychology. Advance online publication. https://doi.org/10.1146/annurev-psych-121024-044244
  • Nahum-Shani, I., & Yoon, C. (2024). Toward the science of engagement with digital interventions. Current Directions in Psychological Science, 33(4), 239–246. https://doi.org/10.1177/09637214241254328 | PubMed
  • Nahum-Shani, I., Dziak, J. J., Venera, H., Pfammatter, A. F., Spring, B., & Dempsey, W. (2024). Design of experiments with sequential randomizations on multiple timescales: The hybrid experimental design. Behavior Research Methods, 56(3), 1770–1792. https://doi.org/10.3758/s13428-023-02119-z | PubMed
  • Nahum-Shani, I., Shaw, S. D., Carpenter, S. M., Murphy, S. A., & Yoon, C. (2022). Engagement in digital interventions. American Psychologist, 77(7), 836–852. https://doi.org/10.1037/amp0000983 | PubMed
  • Nahum-Shani, I., Dziak, J. J., Walton, M. A., & Dempsey, W. (2022). Hybrid experimental designs for intervention development: What, why, and how. Advances in Methods and Practices in Psychological Science, 5(3), Article 25152459221114279. https://doi.org/10.1177/25152459221114279

Funded Research (Active Projects)

  • P50DA054039 (NIH/NIDA), 9/26-5/31; $13.49M
    Methodologies for Adapting and Personalizing Services for SUD (MAPS 2.0)
    PI: Nahum-Shani/Collins/Murphy | Role: Center Director; Contact PI
  • R01MH144636 (NIH/NIMH), 6/26-3/31; $270,266
    An adaptive parent-mediated intervention to improve outcomes for autistic children
    PI: PI: Dai/Zuckerman | Role: Co-Investigator
  • R25CA291583 (NIH/NCI), 8/25-7/30; $1,475,701
    Comprehensive Training in Methods for Adapting and Personalizing Cancer Control Interventions
    PI: Nahum-Shani | Role: Contact PI
  • R01MH139512 (NIH/NIMH), 8/25-7/29; $780,698 (FY1)
    Optimizing the Integration Between Human and Digital Support in a Meditation app for Depression and Anxiety
    PI: Goldberg/Davidson/Nahum-Shani | Role: MPI
  • R01DA058996 (NIH/NIDA), 5/24-2/29; $2,474,085
    Novel Methods to Inform mHealth Interventions for Substance Use
    PI: Ertefaie/Nahum-Shani | Role: MPI
  • HT94252411026 (DoD), 8/24-8/28; $2,400,000
    Changing the Treatment Course: Clinical Trial of Sequenced Interventions to Optimize Treatment for Veterans with PTSD
    PI: LoSavio/Sripada | Role: Co-Investigator
  • R01 GM15254901 (NIH/NIGMS), 3/24-11/27; $1,223,984
    Leveraging ML algorithms and data integration techniques to improve efficiency of causal moderation analyses of micro-randomized trial data
    PI: Dempsey | Role: Co-Investigator
  • R34MH13305701 (NIH/NIMH), 4/24-2/27; $702,000
    Facilitating effective coping to reduce suicide risk following ED discharge: A micro-randomized trial to develop an adaptive text-based intervention
    PI: Czyz/Horwitz | Role: Co-Investigator
  • P50 DA054039 (NIH/NIDA), 9/21-6/26; $13.2M
    Center for Methodologies for Adapting and Personalizing Prevention, Treatment and Recovery Services for SUD and HIV (MAPS Center)
    PI: Nahum-Shani/Almirall/Collins/Murphy | Role: Center Director; Contact PI
  • R01 AA027994 (NIH/NIAAA), 4/21-3/26; $518,547
    Evaluation and optimization of a just-in-time messaging intervention to reduce alcohol-facilitated intimate partner violence perpetration among at-risk young adult men and women
    PI: Stappenbeck | Role: Co-Investigator (Site PI)
  • R01 MH126871 (NIH/NIMH), 7/21-6/26; $151,030
    Adaptive intervention to prevent adolescent suicidal behavior following psychiatric hospitalization: A Sequential Multiple Assignment Randomized Trial
    PI: Czyz | Role: Co-Investigator
  • R01 HD103904 (NIH/NICHD), 7/21-6/26; $191,660
    mHealth-based just-in-time adaptive intervention to improve physical activity levels of individuals with spinal cord injury
    PI: Hiremath | Role: Co-Investigator (Site PI)
  • R01 MH125857 (NIH/NIMH), 12/21-11/26; $129,463
    Testing adaptive interventions to improve PTSD treatment outcomes in federally qualified health centers
    PI: Sripada | Role: Co-Investigator
  • P01 AA029547 (NIH/NIAAA), 6/21-5/26; $419,425
    SHARE Program: Innovations in translational behavioral science to improve self-management of alcohol and HIV in adolescents and emerging adults
    PI: Naar | Role: Co-Investigator (Site PI)
  • U01 CE003382 (CDC), 9/21-9/26; $86,659
    Michigan Youth Violence Prevention Center (YVPC): Building evidence for gun violence prevention
    PI: Zimmerman | Role: Co-Investigator

Recent Talks

  • Innovations in Experimental Designs for Optimizing Adaptive Interventions: An Accessible Introduction to SMARTs, MRTs and Hybrid Designs
    Center for Depression, Anxiety, and Stress Research, Harvard Medical School.
    Harvard University
    June 2026
  • Introduction to SMARTs, MRTs and Hybrid Designs. Training Module 6 (Methodology): Session 1- Understanding Methods and Designs Appropriate for Each Stage
    NIH Stage Trials Training Program
    June 2026
  • Obtaining Funding for Intervention Optimization: Panel Discussion with Funders
    Intervention Optimization Meeting: Science and Practice, Present and Futur
    Bethesda, MD
    May 2026
  • Conundrums, Canards, and Chasms in Intervention Optimization
    Intervention Optimization Meeting: Science and Practice, Present and Futur
    Bethesda, MD
    May 2026
  • Digital Adaptive Interventions: Common Misconceptions and Opportunities
    Mobile Health Training Institute (mHTi)
    April 2026

Contact Info

Address
426 Thompson St, Ann Arbor, MI 48106-1248
Phone
(734) 763-7562
Email
[email protected]