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3. |
Barriers to CNS Drug Delivery / Transporters |
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Course Coordinator: |
B. Elmquist (Nebraska) |
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Faculty Participants: |
B. Elmquist, R. Keep (Michigan), D. Smith (Michigan), K. Audus (Kansas), R. Borchardt (Kansas), D. Miller (Nebraska) |
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Program: |
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12:30 - 1:00 PM |
Lecture 1. Overview of pertinent CNS anatomy/physiology/transport. R. Keep (Michigan) |
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1:00 - 1:30 PM |
Lecture 2. Peptide transporters in the CNS. D. Smith (Michigan) |
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1:30 - 1:45 PM |
Break |
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1:45 - 2:15 PM |
Lecture 3. In vitro models and drug transport in the CNS. K. Audus (Kansas) |
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Lecture 4. Permeability of cyclic peptides in the CNS: a case study. R. Borchardt (Kansas) |
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2:15 - 2:45 PM |
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2:45 - 3:15 PM |
Lecture 5. Second messengers, signal transduction, and the permeability of the BBB. D. Miller (Nebraska) |
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3:15 - 3:45 PM |
Lecture 6. In vivo models and drug transport in the CNS. B. Elmquist (Nebraska) |
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3:45 - 4:00 PM |
Panel Discussion |
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