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| 7. | Dermal / Transdermal Drug Delivery | ||||||
| Course Coordinator: | G. Imanidis (Basel) | ||||||
| Faculty Participants: | G. Imanidis (Basel), G. Flynn (Michigan), R. Guy (Pharmapeptides/U of Geneva), W. Higuchi (U of Utah), M. Roberts (U of Queensland), A. Urtti (U of Kuopio) | ||||||
| Program: | |||||||
| 8:00 - 8:50 AM | Lecture 1. The skin barrier and passive transdermal delivery. G Flynn (Michigan) | ||||||
| 8:50 - 9:40 AM | Lecture 2. Molecular mechanisms of skin permeability and permeation pathways across epidermis (FTIR, DSC, CLSM, Impedance spectroscopy). R. Guy | ||||||
| 9:40 - 9:55 AM | Break | ||||||
| 9:55 - 10:45 AM | Lecture 3. Structure/activity relationship of skin permeation enhancers. W. Higuchi | ||||||
| 10:45 - 11:15 AM | Lecture 4. Structure/permeability relationship of drugs for the skin. M. Roberts | ||||||
| 11:15 - 12:15 PM | Lunch | ||||||
| 12:15 - 1:05 PM | Lecture 5. Cutaneous pharmacokinetics and bioavailability (Modeling, methodology). M. Roberts | ||||||
| 1:05 - 1:25 PM | Lecture 6. The C* Approach. G. Imanidis (Basel) | ||||||
| 1:25 - 1:40 PM | Break | ||||||
| 1:40 - 2:20 PM | Transdermal drug delivery by iontophoresis. R. Guy | ||||||
| 2:20 - 2:50 PM | Insights gained by modeling constant voltage iontophoresis. G. Imanidis (Basel) | ||||||
| 2:50 - 3:20 PM | Cell culture of keratinocytes as a skin model. A. Urtti | ||||||
| 3:20 - 3:50 PM | What does the market place teach about transdermal delivery? G. Flynn (Michigan) | ||||||
| 3:50 - 4:20 PM | Panel Discussion | ||||||