Motor System
- administration of amphetamine also produced greater amounts of rotational behavior in females during estrus in comparison to females in diestrus
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removal of the ovaries (ovariectomy) reduces estrogen levels in female rats and will decrease stereotypy and rotational behavior induced by drugs
associated with this decline in behavior is a decrease in the release of dopamine by amphetamine in ovariectomized females
administration of estrogen to ovariectomized females will enhance dopamine-related behaviors and increase dopamine release within the striatum in response to amphetamine