109 MicroXCT Analysis of Bone Regeneration and Resorption in Tissue-Engineered Constructs

Thursday, March 22, 2012: 8 a.m. - 9:30 a.m.
Presentation Type: Oral Session
P. MITTERMILLER1, S. HO1, S. DJOMEHRI1, W. YU1, A. TOMSIA2, G.W. MARSHALL1, S. MARSHALL1, and J.S. LEE1, 1University of California - San Francisco, San Francisco, CA, 2Lawrence Berkeley National Labs, Berkeley, CA

Objective :  One of the limitations in assessing successful bone regeneration in vivo is the lack of noninvasive high resolution bone quantification methods that allow for multi-modal evaluation of the tissue engineered construct.  We describe a high throughput imaging technique using a 3D micro X-ray computed tomography (µXCT, Micro XCT-200, Xradia, Pleasanton, CA). 

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This abstract is based on research that was funded entirely or partially by an outside source: NIH/BRP and AAOMS Foundation Award # R01 DE015633

Keywords: Bioengineering, Biomaterials, Implants, Regeneration and Remodeling