Potential problems Solutions
Not feasible
Methods inadequate or beyond the skills of the investigator
Too expensive
Not relevant or novel
Uncertain ethical suitability
Consult experts and review the literature for alternative methods
Learn the skills
Collaborate with colleagues who have the skills
Consider less costly study design and measurement methods
Seek additional financial support
Modify the research question
Consult with institutional review board
Modify the research question to avoid potentially unethical elements
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