Rux DR, Song JY, Pineault KM, Mandair GS, Swinehart IT, Schlientz AJ, Garthus KN, Goldstein SA, Kozloff KM, Wellik DM. Hox11 function is required for region-specific fracture repair. Journal of Bone and Mineral Research. 2017
Rux DR, Song JY, Swinehart IT, Pineault KM, Schlientz AJ, Trulik KG, Goldstein SA, Kozloff KM, Lucas D, Wellik DM. Regionally restricted Hox function in adult bone marrow multipotent mesenchymal stem/stromal cells. Dev Cell 2016 39(6)653-666
Perosky JE, Khoury BM, Jenks TN, Ward FS, Cortright K, Meyer B, Barton DK, Sinder BP, Marini JC, Caird MS, Kozloff KM. Single dose of bisphosphonate preserves gains in bone mass following cessation of sclerostin antibody in Brtl/+ osteogenesis imperfecta model. Bone 2016 93:79-85
Scheller EL, Khoury B, Moller KL, Wee NKY, Khandaker S, Kozloff KM, Abrishami SH, Zamarron BF, Singer K: Changes in skeletal integrity and marrow adiposity during high-fat diet and after weight loss. Frontiers in Endocrinology, Bone Research Section 2016 7:102
Youngstron DW, Dishowitz MI, Bales CB, Carr E, Kozloff KM, Shitaye H, Hankenson KD, Loomes KM: Jagged 1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice. Bone 2016 91:64-74
Mertz EL, Makareeva E, Mirigian LS, Koon KY, Perosky JE, Kozloff KM, Leikin S: Makings of a brittle bone: Unexpected lessons from a low protein diet study of a mouse OI model. Matrix Biology 2016 52-54:29-42
Sinder BP, Lloyd WR, Salemi JD, Marini JC, Caird MS, Morris MD, Kozloff KM.: Effect of anti-sclerostin therapy and osteogenesis imperfecta on tissue-level properties in growing and adult mice while controlling for tissue age. Bone 2016 84:222-9
Donneys A, Nelson NS, Perosky J, Polyetskya Y, Rodriguez R, Figueredo C, Vasseli CA, Ratliff HC, Deshpande SS, Kozloff KM, Buchman SR: Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation. Bone 2016 84:245-52
Pineault KM, Swinehart IT, Garthus KN, Ho E, Yao A, Schipani E, Kozloff KM, Wellik DM: Hox 11 genes regulate postnatal longitudinal bone growth and growth plate proliferation. Biology Open 2015 4(11)1538-48
Geister KA, Brinkmeier ML, Cheung LY, Wendt J, Oatley MJ, Burgess DL, Kozloff KM, Cavalcoli JD, Oatley JM, Camper SA: LINE-1 mediated insertion into Poc1a (Protein of Centriole 1A) causes growth insufficiency and male infertility in mice. PLoS Genetics 2015 11(10)e1005569
Feng T, Kozloff KM, Perosky JE, Xu G, Cheng Q, Du S, Yuan J, Deng CX, Wang X: Characterization of bone microstructure using photoacoustic spectrum analysis. Optics Express 2015 23(19)25217-24
Bianchi L, Gagliardi A, Maruelli S, Besio R, Landi C, Gioio R, Kozloff KM, Khoury BM, Symoens S, Coucke P, Marini JC, Rossi A, Bini L, Forlino A: Alterted cytoskeletal organization characterized lethal but not surviving Brtl mice: insight on phenotypic variability in osteogenesis imperfecta. Human Molecular Genetics 2015 24(21)6118-33
Manley E, Perosky JE, Khoury BM, Reddy AB, Kozloff KM, Alford AI: Thrombospondin-2 deficiency alters bone collagen ultrastructure and leads to a brittle bone phenotype. Journal of Applied Physiology 2015 119(8)872-81
Donneys A, Blough JT, Nelson NS, Perosky JE, Deshpande SS, Kang SY, Felice PA, Figueredo C, Peterson JR, Kozloff KM, Levi B, Chepeha DB, Buchman SR: Translational treatment paradigm for managing non-unions secondary to radiation injury utilizing adipose derived stem cells and angiogenic therapy. Head and Neck 2015
Feng T, Kozloff KM, Tian C, Du S, Yuan J, Deng CX, Wang X: Bone assessment via thermal photoactoustic measurements. Optics Letters 2015 40(8): 1721-24
Miedel EL, Brisson BK, Hamilton T, Gleason H, Swain GP, Lopas L, Dopkin D, Perosky JE, Kozloff KM, Hankenson KD, Volk SW: Type III collagen modulates fracture callus bone formation and early remodeling. Journal of Orthopaedic Research 2015 33(5)675-84
Lin GH, Salemi JD, Kozloff KM, Wang HL, Chan HL: Measure bone volume and density changes of sites grafted with bone allografts and a titanium mesh on cone beam computed tomography. Clinical Oral Implants Research 2015 24(3): 362-6
Alford AI, Kozloff KM, Hankenson KD: Extracellular matrix networks in bone remodeling. International Journal of Biochemistry and Cell Biology 2015 65:20-31
Sinder BP, Salemi JD, Caird MS, Marini JC, Kozloff KM: Rapidly growing Brtl/+ mouse model of osteogenesis imperfecta improves bone mass and strength with sclerostin antibody treatment. Bone 2015 71:115-123
Perosky JE, Peterson JR, Eboda ON, Morris MD, Wang SC, Levi B, Kozloff KM Early detection of heterotopic ossification using near-infrared optical imaging reveals dynamic turnover and progression of mineralization following achilles tentomy and burn injury. Journal of Orthopaedic Research 2014 32(11): 1416-1423
Cabral WA, Perdivara I, Weis M, Terajima M, Blissett AR, Chang W, Perosky JE, Makareeva EN, Mertz E, Leikin S, Tomer KB, Kozloff KM, Eyre DR, Yamauchi M, Marini JC Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta. PLoS Genetics 2014 10(6): e1004465.
Sinder BP, White LE, Salemi JD, Ominsky MS, Caird MS, Marini JC, Kozloff KM. Adult Brtl+ mouse model of osteogenesis imperfecta demonstrates anabolic response to sclerostin antibody treatment with increased bone mass and strength. Osteoporosis International 2014 25(8):2097-2107.
Jepsen KJ, Schlecht SH, Kozloff KM. Are we taking full advantage of the growing number of pharmacological treatment options for osteoporosis? Current Opinions in Pharmacology 16: 64-71, 2014
Rodnick ME, Shao X, Kozloff KM, Sherman PS, Scott PJH, Kilboun M. Carbon-11 labeled cathepsin K inhibitors: synthesis and preliminary in vivo evaluation. Nuclear Medicine and Biology 2014 41(5): 384-389
Felice PA, Ahsan S, Perosky JE, Deshpande SS, Nelson NS, Donneys A, Kozloff KM, Buchman SR. Prophylactic amifostine preserves the biomechanical properties of irradiated bone in the murine mandible Plastic and Reconstructive Surgery 2013 133(3):314e-21e.
Meganck JA, Begun DL, McElderry JD, Swick A, Kozloff KM, Goldstein SA, Morris MD, Marini JC, Caird MS. Fracture healing with alendronate treatment in the Brtl/+ mouse model of osteogenesis imperfecta. Bone 2013 56(1): 204-12.
Donneys A, Ahsan S, Perosky JE, Deshpande SS, Tchanque-Fossuo CN, Levi B, Kozloff KM, Buchman SR. Deferoxamine restores callus size, mineralization and mechanical strength in fracture healing after radiotherapy. Plastic and Reconstructive Surgery 2013 131(5):711e-9e.
Peterson JR, Okagbare PI, De La Rosa S, Cilwa KE, Perosky JE, Eboda ON, Donneys A, Su GL, Buchman SR, Cederna PS, Wang SC, Kozloff KM, Morris MD, Levi B: Early detection of burn induced heterotopic ossification using transcutaneous Raman spectroscopy. Bone 2013 54(1): 28-34.
Kuroshima S, Yeh C, Kovacic BL, Kozloff KM, McCauley LK, Yamashita J.: Intraoral PTH administration promotes tooth extraction socket healing. Journal of Dental Research 2013 92(6): 553-9.
Donneys A, Deshpande S, Tchanque-Fossuo C, Johnson K, Blough J, Perosky J, Kozloff KM, Felice P, Nelson N, Farberq A, Levi B, Buchman S.: Deferoxamine expedites consolidation during mandibular distraction osteogenesis. Bone 2013 55(2): 384-90.
Dai J, Zhang H, Karatsinides A, Keller JM, Kozloff KM, Aftab DT, Schimmoller F, Keller ET: Cabozantinib inhibits prostate cancer growth and prevents tumor-induced bone lesions. Clinical Cancer Research 2013 20(3)1-14.
Cho SW, Pirih FQ, Koh AJ, Michalski M, Eber MR, Ritchie K, Sinder B, Oh S, Al-Dujaili SA, Lee J, Kozloff K, Danciu T, Wronski TJ, McCauley LK: The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone. J. Biol. Chem. 2013 288(10): 6814-6825.
Geister KA, Brinkmeier ML, Hsieh M, Faust SM, Karolyi IJ, Perosky J, Kozloff KM, Conti M, Camper SA. A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapeutic for acromesomelic dysplasia, Maroteaux type. Human Molecular Genetics. 2013 22(2)345-57.
Soki FN, Li X, Berry J, Koh A, Sinder BP, Kozloff KM, Taichman R, McCauley LK. The effects of zoledronic acid in the bone and vasculature support of hematopoietic stem cell niches. Journal of Cellular Biochemistry. 2013 114(1)67 -78.
Sinder BP, Eddy MM, Caird MS, Marini JC, Kozloff KM. Sclerostin antibody improves skeletal parameter in a Brtl/+ mouse model of osteogenesis imperfecta. Journal of Bone and Mineral Research. 2013 28(1)73-80.
Novince CM, Entezami P, Wilson CG, Wang J, Oh S, Koh AJ, Michalski MN, Sinder BP, Kozloff KM, Taichman RS, Warman ML, McCauley LK. The impact of proteoglycan-4 and parathryoid hormone on articular cartilage degeneration. Journal of Orthopaedic Research. 2013 31(2)183-90.
Caird MS, Kozloff KM. Bisphosphonate therapy in children. Current Orthopaedic Practice. 2012 23:435-441.
Hoff BA, Chughtai K, Jeon YH, Kozloff K, Galbán S, Rehemtulla A, Ross BD, Galbán CJ: Multimodality imaging of tumor and bone response in a mouse model of bony metastasis. Translational Oncology 2012 5(6): 415-21.
Burke DT, West JL, Wilkowski JM, Kozloff KM, Goldstein SA, Chen S, Miller RA, Galecki AT, Miller RA. Dissection of complex adult traits in a mouse synthetic population. Genome Research 2012 22(8):1549-57.
Hoff BA, Kozloff KM, Boes JL, Galban S, Van Poznak CH, Jacobson JA, Johnson TD, Meyer CR, Rehemtulla A, Ross BD, Galban CJ. Parametric reponse mapping of CT images provide early detection of local bone loss in a rat model of osteoporosis. Bone 2012 51(1):78-84.
M.S. Davis, B.L. Kovacic, J.C. Marini, A.J. Shih, K.M. Kozloff. Increased susceptibility to microdamage in Brtl/+ mouse model for osteogenesis imperfecta. Bone 2012 50:784-791. Cover feature
C. Novince, M. Michalski, B. Sinder, P. Entazami, A. Koh, M. Eber, G. Pettway, T. Rosol, T. Wronski, K.M. Kozloff, L.K. McCauley. Proteoglycan-4: a dynamic regulator of skeletogenesis and PTH skeletal anabolism. Journal of Bone and Mineral Research 2011, doi:10.1002/jbmr.508. [Epub ahead of print].
G.C Goulet, N.R. Halonen, L.G. Koch, S.L. Britton, R.F. Zernicke, K.M. Kozloff. Osteoblast response to ovariectomy is enhanced in intrinsically high aerobic capacity rats. Calcified Tissue International 2011 88(4)325-335
A. Blazeski, K.M. Kozloff, P.J.H. Scott. Besilesomab for imaging inflammation/infection in peripheral bone in adults with suspected osteomyelitis. Reports in Medical Imaging 2010 3:17-27
Hjortnaes J, Butcher J, Figueiredo J, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E. Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodeling: a role for inflammation. European Heart Journal 2010 31:1975-84 Cover feature
Kozloff KM, Volakis LI, Marini JC, Caird MS. Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo. Journal of Bone and Mineral Research 2010 25(8)1748
Meganck JA*, Kozloff KM*, Thornton MM, Broski SM, Goldstein SA. Beam hardening artifacts in micro-computed tomography scanning can be reduced by x-ray beam filtration and the resulting images can be used to accurately measure BMD. Bone 2009 45(6):1104-1116. *Denotes co-first authors
Uveges TE*, Kozloff KM*, Ty J, Ledgard F, Raggio CL, Gronowicz G, Goldstein SA, Marini JC. Alendronate treatment of Brtl osteogenesis imperfecta mouse improves femoral geometry and load response before fracture but decreases predicted material properties and has detrimental efffects on osteoblasts and bone formation. Journal of Bone and Mineral Research 2009 24(5):849-859. *Denotes co-first authors
Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone 2009 44(2):190-8. Cover feature
Kozloff KM, Weissleder R, Mahmood U. Non-invasive optical detection of bone mineral. Journal of Bone and Mineral Research 2007 22(8):1208-16.
Kozloff KM, Carden A, Bergwitz C, Forlino A, Uveges T, Morris MD, Marini JC, Goldstein SA. Brittle mouse model for osteogenesis imperfecta IV demonstrates postpubertal adaptations to improve whole bone strength. Journal of Bone and Mineral Research 2004 19(4):614-622.
McCauley LK, Tozum TF, Kozloff KM, Koh-Paige AJ, Chen C, Demashkieh M, Cronovich H, Richard V, Keller ET, Rosol TJ, Goldstein SA. Transgenic models of metabolic bone disease: Impact of estrogen receptor deficiency on skeletal metabolism. Connective Tissue Research 2003 44(S1): 250-263.
Buchko CJ, Kozloff KM, Martin DC. Surface characterization of porous, biocompatible protein polymer thin films. Biomaterials 2001 22:1289-1300.
Richards M, Kozloff KM, Goulet JA, Goldstein SA. Increased distraction rates influence precursor tissue composition without affecting bone regeneration. Journal of Bone and Mineral Research 2000 15(5)982-989.
Hoffler CE, Moore KE, Kozloff K, Zysset PK, Brown MB, Goldstein SA. Heterogeneity of bone lamellae elastic moduli. Bone 2000 26(6):603-609.
Hoffler CE, Moore KE, Kozloff K, Zysset PK, Goldstein SA. Age, gender and bone lamellae elastic moduli. Journal of Orthopaedic Research 2000 18(3):432-437.
Buchko CJ, Slattery MJ, Kozloff KM, Martin DC. Mechanical properties of biocompatible protein polymer thin films. Journal of Materials Research 2000 15(1):231-242.
Timlin JA, Carden A, Morris MD, Bonadio JF, Hoffler CE, Kozloff KM, Goldstein SA. Spatial distribution of phosphate species in mature and newly generated mammalian bone by hyperspectral Raman imaging. Journal of Biomedical Optics 1999 4(1):28-34.
Carden A, Timlin JA, Edwards CM, Morris MD, Hoffler CE, Kozloff K, Goldstein SA. Raman imaging of bone mineral and matrix: Composition and function. Proceedings of SPIE- The International Society for Optical Engineering 1999 3668:132-138.
