There are three agencies in the US government responsible for regulating biotechnology.  They are: the United States Department of Agriculture (USDA), the Environment Protection Agency (EPA), and the Food and Drug Administration (FDA).

 
The following are regulations that are currently in place.

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57 FR 22984

• Passed on May 29, 1992
• Ensures that new products are safe
• Does not establish special labeling requirements for bio-engineered foods
• Does establish labeling requirements if:

• bio-engineered food is significantly different from its traditional counterpart so that the old name no longer accurately describes the new product
• an issue exists for the food regarding how the food is used or consequences of its use
• bio-engineered food has a significantly different nutritional property
• there is a presence of an allergen that the consumer would not expect to be in the food

58 FR 25837

• Passed on April 28, 1993
• Tried to answer questions raised by 57 FR 22984
• FDA reaffirmed its stance on not requiring special labeling of all genetically modified food
• Also recognized that consumers may not recognize "GM" or "GMO" on label, therefore if a label is required by 57FR 22984, it must be written out "genetically modified" or "genetically engineered"

65 FR 80548

• Passed on December 21, 2000
• Requires that "all but the smallest organic operations" be certified by a USDA accredited agent
• If a food is labeled as "organic" it cannot have been produced using biotechnology methods