YANG RESEARCH GROUP - Recent Publications
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List of recent publications (2002-2007):
(For a more complete list of publications please refer to Extended CV of Dr. Victor C. Yang)
 

115  Yoon-Jeong Park, Jun-Feng Liang, Yong-Tao Li, Sarita Naik, and Victor C. Yang. ATTEMPTS: A Heparin/Protamine-Based Delivery System for Enzyme Drugs. Journal of Controlled Release, 78:67-79 (2002)

116.  Peter Markland, and Victor C. Yang. Biodegradable Polymers as Drug Carriers. Encyclopedia of Pharmaceutical Technology, 2nd Ed. (J. Swarbrick, J.C. Boylan, eds.) pp 136-155, Marcel Dekker, Inc. (2002).

117.  Yuehua Zhang, Zhi-Qiang Yang, Peter Markland, and Victor C. Yang. Poly(glutamic acid) Poly(ethylene glycol)  Hydrogels Prepared by Photo-Induced Polymerization: Synthesis, Characterization, and Preliminary Release Studies of Protein Drugs. Journal of Biomedical Materials Research 62:14-21 (2002).

118.  Yoon Jeong Park, Junfeng Liang, Sarita Naik, and Victor C. Yang. Delivery of Catalytic Macromolecular Drugs. Proceedings of the Third Asian Symposium on Biomaterials & Drug Delivery Systems, R.O.C, in press (2003).

119.   Junfeng Liang, Lan Zhen, Li-Chien Chang, and Victor C. Yang. A Less Toxic Heparin Antagonist: Low Molecular Weight Protamine. Biochemistry (Moscow), 68:139-144 (2003).

120.  An-Rong Lee, Li-Chien Chang, Victor C. Yang, Li-Heng Pao, and Da-Peng Wang. Applications of Polyion-Sensitive Electrodes to Pharmaceutical Domain: A Mini-Review.  Journal of Food and Drug Analysis, 10:212-218 (2003).

121.  Yoon Jeong Park, and Victor C. Yang. Bioconjugates for Effective Drug Targeting. Advanced Drug Delivery Reviews (Park YJ and Yang VC, Theme Eds.), 55:169-170 (2003).

122.  Yoon Jeong Park, Junfeng Liang, Hui Song, Yongtao Li, Sarita Naik, and Victor C. Yang. ATTEMPT: A Heparin/Protamine-Based Triggered Release System for the Delivery of Enzyme Drugs without Associated Side Effects. Advanced Drug Delivery Reviews (Park YJ and Yang VC, Theme Eds.), 55:251-265 (2003).

123.  Yong Tao Li, Jun Feng Liang, and Victor C. Yang. The Use of a Transduction Peptide as a Possible Means for Enzyme Red Blood Cell Encapsulation. American Pharmaceutical Review 6:23-26 (2003).

124.  Yoon Jeong Park, Jun Feng Liang, Kyung Soo Ko, Sung Wan Kim, and Victor C. Yang. Low Molecular Weight Protamine as an Efficient and Nontoxic Gene Carrier. Journal of Gene Medicine, 5:700-711 (2003).

125.  Yoon Jeong Park, Sook Hee Nah, Jue Yeon Lee, Jae Min Jeong, Jun Key Chung, Myung Chul Lee, Victor C. Yang, and Seung Jin Lee. Surface-modified Poly(lactic-co-glycolide) Nanospheres for Targeted Bone Imaging with Enhanced Labeling and Delivery of Radioisotope. Journal of Biomedical Materials Research, 67A:751-760 (2003).

126.  Jun Feng Liang, Yoon Jeong Park, Jin Chang, and Victor C. Yang. ATTEMPTS: A Pharmaceutical Engineering Approach for Delivery of Macromolecular Drugs. Frontiers in Biomedical Engineering (Ned Huang, Peter Taijan, Eds.) Kluwer Academic Publisher, New York, pp. 168-178 (2004).

127.  Pen-Chung Chen, Yoon Jeong Park, Li-Chien Chang, Robert H. Bartlett, and Victor C. Yang. Injectable Microparticle-Gel System for Prolonged and Localized Lidocain Release (I): In Vitro Characterization.  Journal of Biomedical Materials Research, 70A:412-419 (2004).

128.  Pen-Chung Chen, Daniel S. Kohane, Yoon Jeong Park, Robert H. Bartlett, Robert Langer, and Victor C. Yang. Injectable Microparticle-Gel System for Prolonged and Localized Lidocain Release (II): In Vivo Anesthetic Effects.  Journal of Biomedical Materials Research 70A:459-466 (2004).

129.  Junfeng Liang, Emel Emregul, and Victor C. Yang. Development of a Protamine-Hollow Fiber Device for Extracorporeal Heparin Removal.  Blood Purification 22:198-202 (2004).

130.  Yongtao Li, Junfeng Liang, Yoon Jeong Park, Sarita S. Naik, Young Min Kwon, and Victor C. Yang. An Innovative PTD-Mediated Protein Transduction Therapy for Cancer Treatment. Proceedings of the 4th Asian Symposium on Biomaterials and Drug Delivery Systems, PP147-151 (2004).

131.  Sarita Naik, Hui Song, Yoon Jeong Park, Junfeng Liang, and Victor C. Yang. Application of the ATTEMPTS for Drug Delivery.  Journal of Controlled Release, 101:35-45 (2004).

132.  Li-Chien Chang, Hsiao Feng Lee, Meng Ju Chung, and Victor C. Yang.  PEG-Modified Protamine with Improved Pharmacological/Pharmaceutical Properties as a Potential Protamine Substitute: Synthesis and In Vitro Evaluation.  Bioconjugate Chemistry 16:147-155 (2005).

133.  Yoon Jeong Park, Junfeng Liang, and Victor C. Yang. Nontoxic Membrane Translocation Peptide from Protamine, LMWP, for Enhanced Intracellular Drug Delivery: In Vitro and In Vivo Studies. FASEB Journal, 19:1555-1557 (2005).

134.  Emel Emregul, Alan David, Joseph P. Balthasar, and Victor C. Yang.  A GPIIb/IIIa Bioreactor for Specific Treatment of Immune Thrombocytopenic Purpura (ITP), an Autoimmune Disease.  Preparation, In Vitro Characterization, and Preliminary Proof-of-Concept Animal Studies. Journal of Biomedical Materials Research, 75A:648-655 (2005).

135.  Victor C. Yang, Sarita Naik, Hui Song, Alan Dombkowski, Gordon Crippen, and Jun F. Liang. Engineering of Heparin-Binding t-PA Mutants for Potential Application in Thrombolytic Therapy without Associated Bleed Risks.  Journal of Controlled Release, 110:164-176 (2005).

136.  Tanya Wang, Zhiqiang Yang, Emel Emregul, Allan David, Joseph P. Balthasar, Junfeng Liang, and Victor C. Yang. Strategies for Improving the Functionality of an Affinity Type Bioreactor.  International Journal of Pharmaceutics, 306:132-141 (2005).

137.  Jun Feng Liang, Victor C. Yang, and Yekaterina Vaynshteyn.  The Minimal Functional Sequence of Protamine.  Biophysical and Biochemical Research Communication, 336:653-659 (2005).

138.  Junfeng Liang, and Victor C. Yang. Synthesis of Doxorubicin-Peptide Conjugate with Multidrug Resistant Tumor-Killing Activity. Bioorganic & Medicinal Chemistry Letters, 15:5071-5075 (2005).

139.  Jun Feng Liang, and Victor C. Yang.  Insulin-Cell Penetrating Peptide Hybrids with Improved Intestinal Absorption Efficiency. Biophysical and Biochemical Research Communication, 335:734-738 (2005).

140.  Victor C. Yang, Young Min Kwon, and Yoon Jeong Park. Delivery of Macromolecular Drugs: From ATTEMPTS Approach to PTD-Mediated Cellular Delivery.  Proceedings of the 7th International Symposium on Peptides and Biomaterials for Tissue Regeneration, pp. 5-9 (2005).

141.  Victor C. Yang. ''The ATTEMPTS Approach for Delivery of Macromolecular Drugs.'' Proceedings of the China-Japan Symposium on Pharmaceutical Preparations and Particulate Design, pp. 14-17 (2006).

142.  Allan David, Victor C. Yang, and Arthur J. Yang. Chemically Surface Modified Gel (CSMG): An Excellent Enzyme Immobilization Matrix for Industrial Processes.  Journal of Biotechnology, 125:395-407 (2006).

143.  Victor C. Yang. ''Strategies for Developing Macromolecular Therapeutic Agents.'' Proceedings of the 282th Xiang Shan Meeting, pp. 4-11, Xiang Shan, China (2006).

144.  Jin-Shuen Chen, De Chuan Chan, Meng Ju Chung, Yu-Feng Lin, Victor C. Yang, and Li-Chien Chang. Abnormality in Postoperative Fibrinolytic Activities for Cancer and Uremic Patients.  Blood, submitted (2006).

145.  Choel Moon, Young Min Kwon, Won Kyu Lee, Yoon Jeong Park, Li-Chien Chang, and Victor C. Yang.  A Novel Polyrotaxane-Based Intracellular Delivery System for Camptothecin: In Vitro Feasibility Evaluation.  Submitted to Journal of Biomedical Materials Research (2007).

146.  Choel Moon, Young Min Kwon, Won Kyu Lee, Yoon Jeong Park, and Victor C. Yang.  A Polyrotaxane-Based System for Intracellular Delivery of Doxorubicin.  Submitted to Journal of Controlled Release (2007).

147.  Beata Chertok, Bradford A. Moffat, Allan E. David, Faquan Yu, Christian Bergemann, Brain Ross, and Victor C. Yang.  Magnetic Nanoparticles as an MRI-visiblevehicle ffor Magnetically Targeted Drug Delivery to Brain Tumors.  Submitted to Clinical Cancer Research (2007).

148.  Yongtao Li, Jun Feng Liang, Yoon Jeong Park, Young Min Kwon, and Victor C. Yang. Protein Transduction Domain (PTD)-Mediated Asparaginase Therapy. [I] In Vitro Characterization.  to Bioconjugate Chemistry (2007).

149.  Yongtao Li, Hongfang Wang, Gerald J. Spangrude, Jun Feng Liang, Yoon Jeong Park, Young Min Kwon, and Victor C. Yang. Protein Transduction Domain (PTD)-Mediated Asparaginase Therapy. [II] In Vivo Proof-of-Concept Study.  To be submitted to Bioconjugate Chemistry (2007).

150.  Young Min Kwon, Hee Sun Chung, Yoon Jeong Park, and Victor C. Yang. A Novel Method for Red Blood Cell Encapsulation of Protein Drugs. To be submitted to Nature Methods (2007).