.. _C9orf53:

C9orf53
^^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: chromosome 9 open reading frame 53
:Entrez Gene ID: 51198
:Location: 9p21.3
:Synonyms: bA149I2.3
:Type: miscRNA

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+------------+---------------+------------+
|    SNP     | Distance (bp) | Direction  |
+============+===============+============+
| rs10811661 |     166341    | downstream |
+------------+---------------+------------+

.. _C9orf53 Gene summary:

NCBI Summary
************

None available.

.. _C9orf53 OMIM Text:

OMIM
****

No OMIM data available for this gene.

.. _C9orf53 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _C9orf53 GO Term:

Gene Ontology
*************

No GO terms found linked to this gene.

.. _C9orf53 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _C9orf53 GeneRIF:

GeneRIFs
********

* The C allele of rs1333049 in the vascular disease susceptibility locus is associated with vascular dementia and late-onset Alzheimer's disease, independent of traditional risk factors. [`PMID 19664850`_]
* Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction. [`PMID 21385355`_]
* A chromosome 9p21.3 variant predicts the risk of myocardial infarction among white men. [`PMID 21406102`_]
* Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) [`PMID 21048031`_]

.. _PMID 19664850: http://www.ncbi.nlm.nih.gov/pubmed/19664850
.. _PMID 21385355: http://www.ncbi.nlm.nih.gov/pubmed/21385355
.. _PMID 21406102: http://www.ncbi.nlm.nih.gov/pubmed/21406102
.. _PMID 21048031: http://www.ncbi.nlm.nih.gov/pubmed/21048031

.. _C9orf53 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Emanuele E et al. "Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease." Neurobiol Aging. 2011 Jul;32(7):1231-5. `PMID 19664850`_
* Shiffman D et al. "The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study." BMC Cardiovasc Disord. 2011 Mar 15;11:10. `PMID 21406102`_
* Scheffold T et al. "Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry." BMC Cardiovasc Disord. 2011 Mar 7;11:9. `PMID 21385355`_
* Casabonne D et al. "Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph." Haematologica. 2011 Feb;96(2):323-7. `PMID 21048031`_
* Olsen JV et al. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Cell. 2006 Nov 3;127(3):635-48. `PMID 17081983`_
* Humphray SJ et al. "DNA sequence and analysis of human chromosome 9." Nature. 2004 May 27;429(6990):369-74. `PMID 15164053`_

.. _PMID 19664850: http://www.ncbi.nlm.nih.gov/pubmed/19664850
.. _PMID 17081983: http://www.ncbi.nlm.nih.gov/pubmed/17081983
.. _PMID 15164053: http://www.ncbi.nlm.nih.gov/pubmed/15164053
.. _PMID 21048031: http://www.ncbi.nlm.nih.gov/pubmed/21048031
.. _PMID 21385355: http://www.ncbi.nlm.nih.gov/pubmed/21385355
.. _PMID 21406102: http://www.ncbi.nlm.nih.gov/pubmed/21406102