.. _DHTKD1:

DHTKD1
^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: dehydrogenase E1 and transketolase domain containing 1
:Entrez Gene ID: 55526
:Location: 10p14
:Synonyms: 
:Type: protein-coding

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+------------+---------------+------------+
|    SNP     | Distance (bp) | Direction  |
+============+===============+============+
| rs12779790 |     162786    | downstream |
+------------+---------------+------------+

.. _DHTKD1 Gene summary:

NCBI Summary
************

None available.

.. _DHTKD1 OMIM Text:

OMIM
****

No OMIM data available for this gene.

.. _DHTKD1 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _DHTKD1 GO Term:

Gene Ontology
*************

* thiamine pyrophosphate binding
* mitochondrion
* oxoglutarate dehydrogenase (succinyl-transferring) activity
* tricarboxylic acid cycle
* glycolysis

.. _DHTKD1 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _DHTKD1 GeneRIF:

GeneRIFs
********

* Observational study of gene-disease association. (HuGE Navigator) [`PMID 20877624`_]

.. _PMID 20877624: http://www.ncbi.nlm.nih.gov/pubmed/20877624

.. _DHTKD1 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Flachsbart F et al. "Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study." Mutat Res. 2010 Dec 10;694(1-2):13-9. `PMID 20800603`_
* Hendrickson SL et al. "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression." PLoS One. 2010 Sep 21;5(9):e12862. `PMID 20877624`_
* Wang AG et al. "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." Biochem Biophys Res Commun. 2006 Jul 7;345(3):1022-32. `PMID 16712791`_
* Grupe A et al. "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." Am J Hum Genet. 2006 Jan;78(1):78-88. `PMID 16385451`_
* Strausberg RL et al. "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. `PMID 12477932`_
* Nagase T et al. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." DNA Res. 2000 Aug 31;7(4):273-81. `PMID 10997877`_
* Hillier LD et al. "Generation and analysis of 280,000 human expressed sequence tags." Genome Res. 1996 Sep;6(9):807-28. `PMID 8889549`_

.. _PMID 12477932: http://www.ncbi.nlm.nih.gov/pubmed/12477932
.. _PMID 20877624: http://www.ncbi.nlm.nih.gov/pubmed/20877624
.. _PMID 20800603: http://www.ncbi.nlm.nih.gov/pubmed/20800603
.. _PMID 10997877: http://www.ncbi.nlm.nih.gov/pubmed/10997877
.. _PMID 16385451: http://www.ncbi.nlm.nih.gov/pubmed/16385451
.. _PMID 8889549: http://www.ncbi.nlm.nih.gov/pubmed/8889549
.. _PMID 16712791: http://www.ncbi.nlm.nih.gov/pubmed/16712791

*Top Pubmed articles linked to gene DHTKD1 matching any search term:* 

* Flachsbart F et al. "Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study." Mutat Res. 2010 Dec 10;694(1-2):13-9. `PMID 20800603`_

.. _PMID 20800603: http://www.ncbi.nlm.nih.gov/pubmed/20800603