.. _FAT3:

FAT3
^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: FAT tumor suppressor homolog 3 (Drosophila)
:Entrez Gene ID: 120114
:Location: 11q14.3
:Synonyms: CDHR10, CDHF15
:Type: protein-coding

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+------------+---------------+------------+
|    SNP     | Distance (bp) | Direction  |
+============+===============+============+
| rs10830963 |     79075     | downstream |
+------------+---------------+------------+

.. _FAT3 Gene summary:

NCBI Summary
************

None available.

.. _OMIM ID 612483
                        : http://omim.org/entry/612483
                        

.. _FAT3 OMIM Text:

OMIM
****

:OMIM ID: `OMIM ID 612483
                        `_


.. _FAT3 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _FAT3 GO Term:

Gene Ontology
*************

* calcium ion binding
* plasma membrane
* multicellular organismal development
* homophilic cell adhesion
* integral to membrane

.. _FAT3 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _FAT3 GeneRIF:

GeneRIFs
********

* Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) [`PMID 20379614`_]
* Affinity Capture-MS [`PMID 21875946`_]

.. _PMID 20379614: http://www.ncbi.nlm.nih.gov/pubmed/20379614
.. _PMID 21875946: http://www.ncbi.nlm.nih.gov/pubmed/21875946

.. _FAT3 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Berndt JD et al. "Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling." J Cell Biol. 2011 Sep 5;194(5):737-50. `PMID 21875946`_
* Rose JE et al. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." Mol Med. 2010 Jul-Aug;16(7-8):247-53. `PMID 20379614`_
* Wu Q et al. "Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes." Genetics. 2005 Apr;169(4):2179-88. `PMID 15744052`_
* Brandenberger R et al. "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation." Nat Biotechnol. 2004 Jun;22(6):707-16. `PMID 15146197`_
* Ota T et al. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat Genet. 2004 Jan;36(1):40-5. `PMID 14702039`_
* Strausberg RL et al. "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. `PMID 12477932`_
* Mitsui K et al. "Mammalian fat3: a large protein that contains multiple cadherin and EGF-like motifs." Biochem Biophys Res Commun. 2002 Feb 1;290(4):1260-6. `PMID 11811999`_

.. _PMID 15744052: http://www.ncbi.nlm.nih.gov/pubmed/15744052
.. _PMID 14702039: http://www.ncbi.nlm.nih.gov/pubmed/14702039
.. _PMID 15146197: http://www.ncbi.nlm.nih.gov/pubmed/15146197
.. _PMID 12477932: http://www.ncbi.nlm.nih.gov/pubmed/12477932
.. _PMID 20379614: http://www.ncbi.nlm.nih.gov/pubmed/20379614
.. _PMID 11811999: http://www.ncbi.nlm.nih.gov/pubmed/11811999
.. _PMID 21875946: http://www.ncbi.nlm.nih.gov/pubmed/21875946