.. _FCHSD2:

FCHSD2
^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: FCH and double SH3 domains 2
:Entrez Gene ID: 9873
:Location: 11q13.4
:Synonyms: SH3MD3, NWK
:Type: protein-coding

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+-----------+---------------+------------+
|    SNP    | Distance (bp) | Direction  |
+===========+===============+============+
| rs1552224 |     114692    | downstream |
+-----------+---------------+------------+

.. _FCHSD2 Gene summary:

NCBI Summary
************

None available.

.. _FCHSD2 OMIM Text:

OMIM
****

No OMIM data available for this gene.

.. _FCHSD2 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _FCHSD2 GO Term:

Gene Ontology
*************

* protein binding

.. _FCHSD2 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _FCHSD2 GeneRIF:

GeneRIFs
********

* Affinity Capture-Western; Reconstituted Complex; Two-hybrid [`PMID 14627983`_]
* Reconstituted Complex [`PMID 14627983`_]
* Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) [`PMID 20379614`_]
* Two-hybrid [`PMID 22558309`_]
* Two-hybrid [`PMID 22558309`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Affinity Capture-Western; Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 18654987`_]
* Two-hybrid [`PMID 16189514`_]
* Two-hybrid [`PMID 16189514`_]

.. _PMID 14627983: http://www.ncbi.nlm.nih.gov/pubmed/14627983
.. _PMID 20379614: http://www.ncbi.nlm.nih.gov/pubmed/20379614
.. _PMID 22558309: http://www.ncbi.nlm.nih.gov/pubmed/22558309
.. _PMID 18654987: http://www.ncbi.nlm.nih.gov/pubmed/18654987
.. _PMID 16189514: http://www.ncbi.nlm.nih.gov/pubmed/16189514

.. _FCHSD2 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Wong KA et al. "Intersectin (ITSN) family of scaffolds function as molecular Hubs in protein interaction networks." PLoS One. 2012;7(4):e36023. `PMID 22558309`_
* Rose JE et al. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." Mol Med. 2010 Jul-Aug;16(7-8):247-53. `PMID 20379614`_
* Thalappilly S et al. "Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach." Proteomics. 2008 Aug;8(15):3071-81. `PMID 18654987`_
* Taylor TD et al. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature. 2006 Mar 23;440(7083):497-500. `PMID 16554811`_
* Rual JF et al. "Towards a proteome-scale map of the human protein-protein interaction network." Nature. 2005 Oct 20;437(7062):1173-8. `PMID 16189514`_
* Gerhard DS et al. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 2004 Oct;14(10B):2121-7. `PMID 15489334`_
* Murwantoko et al. "Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease." Biochem J. 2004 Aug 1;381(Pt 3):895-904. `PMID 15101818`_
* Katoh M et al. "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico." Int J Mol Med. 2004 May;13(5):749-54. `PMID 15067381`_
* Coyle IP et al. "Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila." Neuron. 2004 Feb 19;41(4):521-34. `PMID 14980202`_
* Ohno H et al. "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains." Oncogene. 2003 Nov 20;22(52):8422-31. `PMID 14627983`_

.. _PMID 14980202: http://www.ncbi.nlm.nih.gov/pubmed/14980202
.. _PMID 16554811: http://www.ncbi.nlm.nih.gov/pubmed/16554811
.. _PMID 16189514: http://www.ncbi.nlm.nih.gov/pubmed/16189514
.. _PMID 15101818: http://www.ncbi.nlm.nih.gov/pubmed/15101818
.. _PMID 18654987: http://www.ncbi.nlm.nih.gov/pubmed/18654987
.. _PMID 15067381: http://www.ncbi.nlm.nih.gov/pubmed/15067381
.. _PMID 14627983: http://www.ncbi.nlm.nih.gov/pubmed/14627983
.. _PMID 20379614: http://www.ncbi.nlm.nih.gov/pubmed/20379614
.. _PMID 22558309: http://www.ncbi.nlm.nih.gov/pubmed/22558309
.. _PMID 15489334: http://www.ncbi.nlm.nih.gov/pubmed/15489334