.. _MIR3150B:

MIR3150B
^^^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: microRNA 3150b
:Entrez Gene ID: 100500907
:Location: 8
:Synonyms: 
:Type: miscRNA

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+----------+---------------+------------+
|   SNP    | Distance (bp) | Direction  |
+==========+===============+============+
| rs896854 |     124628    | downstream |
+----------+---------------+------------+

.. _MIR3150B Gene summary:

NCBI Summary
************

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

.. _MIR3150B OMIM Text:

OMIM
****

No OMIM data available for this gene.

.. _MIR3150B Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _MIR3150B GO Term:

Gene Ontology
*************

No GO terms found linked to this gene.

.. _MIR3150B Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _MIR3150B GeneRIF:

GeneRIFs
********

None available.

.. _MIR3150B Pubmed:

PubMed Articles
***************

*Recent articles:*

* Schotte D et al. "Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia." Leukemia. 2011 Sep;25(9):1389-99. `PMID 21606961`_
* Persson H et al. "Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene." Cancer Res. 2011 Jan 1;71(1):78-86. `PMID 21199797`_
* Creighton CJ et al. "Discovery of novel microRNAs in female reproductive tract using next generation sequencing." PLoS One. 2010 Mar 10;5(3):e9637. `PMID 20224791`_
* Griffiths-Jones S et al. "miRBase: microRNA sequences, targets and gene nomenclature." Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4. `PMID 16381832`_

.. _PMID 16381832: http://www.ncbi.nlm.nih.gov/pubmed/16381832
.. _PMID 20224791: http://www.ncbi.nlm.nih.gov/pubmed/20224791
.. _PMID 21606961: http://www.ncbi.nlm.nih.gov/pubmed/21606961
.. _PMID 21199797: http://www.ncbi.nlm.nih.gov/pubmed/21199797