.. _MIR548A2:

MIR548A2
^^^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: microRNA 548a-2
:Entrez Gene ID: 693126
:Location: 6
:Synonyms: MIRN548A2
:Type: miscRNA

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+-----------+---------------+-----------+
|    SNP    | Distance (bp) | Direction |
+===========+===============+===========+
| rs4607103 |       0       |   within  |
+-----------+---------------+-----------+

.. _MIR548A2 Gene summary:

NCBI Summary
************

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

.. _MIR548A2 OMIM Text:

OMIM
****

No OMIM data available for this gene.

.. _MIR548A2 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _MIR548A2 GO Term:

Gene Ontology
*************

No GO terms found linked to this gene.

.. _MIR548A2 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _MIR548A2 GeneRIF:

GeneRIFs
********

None available.

.. _MIR548A2 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Landgraf P et al. "A mammalian microRNA expression atlas based on small RNA library sequencing." Cell. 2007 Jun 29;129(7):1401-14. `PMID 17604727`_
* Cummins JM et al. "The colorectal microRNAome." Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3687-92. `PMID 16505370`_
* Griffiths-Jones S et al. "miRBase: microRNA sequences, targets and gene nomenclature." Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4. `PMID 16381832`_

.. _PMID 17604727: http://www.ncbi.nlm.nih.gov/pubmed/17604727
.. _PMID 16381832: http://www.ncbi.nlm.nih.gov/pubmed/16381832
.. _PMID 16505370: http://www.ncbi.nlm.nih.gov/pubmed/16505370