.. _PDZD4:

PDZD4
^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: PDZ domain containing 4
:Entrez Gene ID: 57595
:Location: Xq28
:Synonyms: LU1, PDZK4, PDZRN4L
:Type: protein-coding

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+-----------+---------------+------------+
|    SNP    | Distance (bp) | Direction  |
+===========+===============+============+
| rs3020789 |     174636    | downstream |
+-----------+---------------+------------+

.. _PDZD4 Gene summary:

NCBI Summary
************

None available.

.. _OMIM ID 300634
                        : http://omim.org/entry/300634
                        

.. _PDZD4 OMIM Text:

OMIM
****

:OMIM ID: `OMIM ID 300634
                        `_


.. _PDZD4 Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _PDZD4 GO Term:

Gene Ontology
*************

* cell cortex

.. _PDZD4 Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _PDZD4 GeneRIF:

GeneRIFs
********

* PDZRN4L showed 49.9% total-amino-acid identity with PDZRN4 short isoform (PDZRN4S). PDZ, PR34H1 and PR34H2 domains were conserved between PDZRN4L and PDZRN4S. [`PMID 15138636`_]
* Might play an important role in the proliferation of SS cells and might be a suitable target for SS drugs. [`PMID 15077175`_]

.. _PMID 15138636: http://www.ncbi.nlm.nih.gov/pubmed/15138636
.. _PMID 15077175: http://www.ncbi.nlm.nih.gov/pubmed/15077175

.. _PDZD4 Pubmed:

PubMed Articles
***************

*Recent articles:*

* Lim J et al. "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." Cell. 2006 May 19;125(4):801-14. `PMID 16713569`_
* Gerhard DS et al. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 2004 Oct;14(10B):2121-7. `PMID 15489334`_
* Nagayama S et al. "Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas." Oncogene. 2004 Jul 15;23(32):5551-7. `PMID 15077175`_
* Katoh M et al. "Identification and characterization of human PDZRN4L gene and mouse Pdzrn4l gene in silico." Int J Mol Med. 2004 Jun;13(6):923-7. `PMID 15138636`_
* Ota T et al. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat Genet. 2004 Jan;36(1):40-5. `PMID 14702039`_
* Strausberg RL et al. "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. `PMID 12477932`_
* Nagase T et al. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." DNA Res. 2000 Apr 28;7(2):143-50. `PMID 10819331`_
* Sandoval N et al. "The genomic organization of a human creatine transporter (CRTR) gene located in Xq28." Genomics. 1996 Jul 15;35(2):383-5. `PMID 8661155`_

.. _PMID 14702039: http://www.ncbi.nlm.nih.gov/pubmed/14702039
.. _PMID 12477932: http://www.ncbi.nlm.nih.gov/pubmed/12477932
.. _PMID 10819331: http://www.ncbi.nlm.nih.gov/pubmed/10819331
.. _PMID 8661155: http://www.ncbi.nlm.nih.gov/pubmed/8661155
.. _PMID 16713569: http://www.ncbi.nlm.nih.gov/pubmed/16713569
.. _PMID 15138636: http://www.ncbi.nlm.nih.gov/pubmed/15138636
.. _PMID 15077175: http://www.ncbi.nlm.nih.gov/pubmed/15077175
.. _PMID 15489334: http://www.ncbi.nlm.nih.gov/pubmed/15489334