.. _SLC22A18AS:

SLC22A18AS
^^^^^^^^^^

.. contents::
   :local:

General Information
*******************

:Full gene name: solute carrier family 22 (organic cation transporter), member 18 antisense
:Entrez Gene ID: 5003
:Location: 11p15.5
:Synonyms: BWR1B, SLC22A1LS, ORCTL2S, BWSCR1B, p27-BWR1B
:Type: protein-coding

User SNPs
*********

SNPs given by the user that are near or inside this gene: 

+-----------+---------------+------------+
|    SNP    | Distance (bp) | Direction  |
+===========+===============+============+
| rs2237892 |     69576     | downstream |
+-----------+---------------+------------+
|  rs231362 |     217856    | downstream |
+-----------+---------------+------------+

.. _SLC22A18AS Gene summary:

NCBI Summary
************

None available.

.. _OMIM ID 603240
                        : http://omim.org/entry/603240
                        

.. _SLC22A18AS OMIM Text:

OMIM
****

:OMIM ID: `OMIM ID 603240
                        `_


.. _SLC22A18AS Phenotype:

NCBI Phenotypes
***************

No phenotypes found linked to this gene.

.. _SLC22A18AS GO Term:

Gene Ontology
*************

* molecular_function
* cellular_component
* biological_process

.. _SLC22A18AS Pathway:

KEGG Pathways
*************

No pathways found linked to this gene.

.. _SLC22A18AS GeneRIF:

GeneRIFs
********

* Results suggest imprinting of the paternal allele of SLC22A1LS gene in five fetal tissues: brain, liver, placenta, kidneys and lungs. [`PMID 15175115`_]
* SLC22A18/SLC22A18AS genes are a sense-antisense pair located at human chromosome segment 11p15.5. These genes are paternally imprinted. [`PMID 18721868`_]
* Using antibodies generated in rabbit, immunoprecipitation and Western blot analyses, translation of a 253-aa ORF at very low levels occurred. The translated protein was mainly localized in the cytoplasm. [`PMID 18721868`_]

.. _PMID 15175115: http://www.ncbi.nlm.nih.gov/pubmed/15175115
.. _PMID 18721868: http://www.ncbi.nlm.nih.gov/pubmed/18721868

.. _SLC22A18AS Pubmed:

PubMed Articles
***************

*Recent articles:*

* Bajaj V et al. "Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS." Gene. 2008 Nov 15;424(1-2):40-7. `PMID 18721868`_
* Gerhard DS et al. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 2004 Oct;14(10B):2121-7. `PMID 15489334`_
* Bajaj V et al. "Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5." BMC Genet. 2004 Jun 3;5:13. `PMID 15175115`_
* Strausberg RL et al. "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. `PMID 12477932`_
* Cooper PR et al. "Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain." Genomics. 1998 Apr 1;49(1):38-51. `PMID 9570947`_
* Schwienbacher C et al. "Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples." Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3873-8. `PMID 9520460`_

.. _PMID 9520460: http://www.ncbi.nlm.nih.gov/pubmed/9520460
.. _PMID 18721868: http://www.ncbi.nlm.nih.gov/pubmed/18721868
.. _PMID 12477932: http://www.ncbi.nlm.nih.gov/pubmed/12477932
.. _PMID 9570947: http://www.ncbi.nlm.nih.gov/pubmed/9570947
.. _PMID 15175115: http://www.ncbi.nlm.nih.gov/pubmed/15175115
.. _PMID 15489334: http://www.ncbi.nlm.nih.gov/pubmed/15489334