MIR3150A

General Information

Full gene name:microRNA 3150a Entrez Gene ID:100422964 Location:8 Synonyms:MIR3150 Type:miscRNA

User SNPs

SNPs given by the user that are near or inside this gene:

SNP	Distance (bp)	Direction
rs896854	124631	upstream

NCBI Summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM

No OMIM data available for this gene.

NCBI Phenotypes

No phenotypes found linked to this gene.

Gene Ontology

No GO terms found linked to this gene.

KEGG Pathways

No pathways found linked to this gene.

GeneRIFs

None available.

PubMed Articles

Recent articles:

• Persson H et al. “Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene.” Cancer Res. 2011 Jan 1;71(1):78-86. PMID 21199797
• Stark MS et al. “Characterization of the Melanoma miRNAome by Deep Sequencing.” PLoS One. 2010 Mar 12;5(3):e9685. PMID 20300190
• Griffiths-Jones S et al. “miRBase: microRNA sequences, targets and gene nomenclature.” Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4. PMID 16381832