CLUSTAL 2.1 multiple sequence alignment


3               MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKKLDAKY-----KKGGA
5               MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKKLDAKY-----KKGGA
1               MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKQLDAKY-----KKGGA
4               ------------------------------------------------------------
106             MAKVRVYEYAKAIDVSSKDIIAALKDMNVEVNNHMATLEDDTVKKLDAIY-----KKAKA
2               ------------------------------------------------------------
101             MSKMRVYEYAKKLNKSSKEIITKLTENNIEVANHMSMIDENAIKILDTAYTTNNEKTQAK
105             ------------------------------------------------------------
103             MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEY-------QAE
102             MRKIRIYEYAKEKNVTSKQVIKDLKDMGIEVANHMSVIQGDTIEKLDKTYSQSVKTEEKA
100             MKKMRIYEYAKEKNVSSKEVIDKLKSLNMDVTNHMSVIDDKMVALLDGDSKQKKPATDAS
104             MSKVRIYEYAKANNVQSKQLIESLKSMGVEVSNHMSAIDEETLNKAKQAGKPAAAKGQGS
                                                                            

3               AAKS-QKPAETNKNKQPQGVNQQSAGNQPNKIRD--------------------------
5               AAKS-QKPAETNKNKQPQGVNQQSAGNQPNKIRD--------------------------
1               AAKS-QKPAETNKNKQPQGINQQSAGNQPNKIRD--------------------------
4               ------------------------------------------------------------
106             KETTNEKPAEQKK---------QSS----NKNND--------------------------
2               ------------------------------------------------------------
101             KSESNKQKPEQKKTKKEPILPSTDQSDSDNSDDDKYNYDNKK----------------AK
105             ------------------------------------------------------------
103             KPS---------------------------------------------------------
102             KDTKTTQGSTGKQNNAPQQGKNKQQQE---------------------------------
100             KDNKAQNRTN-KPNQSNNQAPQNRNQKNKPKQ----------------------------
104             TSNQKQNSQNQRSNQGQKQRPQNNQQNQGQKQRPQNNQQSQSQGQTKRPSQASNNQSGAA
                                                                            

3               --GKKNDVQNNQFNKN---------KKNNNNKKNK-RNNNNNKNQHQQK-PVKPKKELPE
5               --GKKNDVQNNQFNKN---------KKNNNNKKNK-RNNNNNKNQHQQK-PVKPKKELPE
1               --GKKNDVQNNQFNKN---------KKNNNNKKNK-RNHNN-KNQHQQK-PVKPKKELPE
4               ------------------------------------------------------------
106             --RKKNDVQNNQFNKN---------KKNNNQNKNKNKRGGNNKSQHQQARPVKPKKELPE
2               ------------------------------------------------------------
101             GPKKVKAKQDKEKDKT---------ADNKITKQNPKNKRQHPNHQHQQNQQQAPKNEESA
105             --------MNKNTKST---------ANKGNNKGNKKPQAQKSQAPKGRPAPAAAK-ELPE
103             --VADEFEVEEKVVRS---------KKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPD
102             --KPTKKQQSKENHDK---------NKNKDKNKNKNRRGDKQKSQSTKQEAKTPVKETPS
100             ----GKGPQNRSNKGP---------NKR---NQTQQNHTPP----KPK--------PLPE
104             KSQAGKPNQNRGGNRPGGQGRPGSNNRRPGNNQNRRNHGNRGGKRRPQSKVNHQQMPLPE
                                                                            

3               KIT-FSGTLTVGALAEELGKEPSEIIKKLMLLGVMATINQELDKDTIELIASEYGVETEE
5               KIT-FSGTLTVGALAEELGKEPSELIKKLMLLGVMATINQELDKDTIELIASEYGVETEE
1               KIT-FSGTLTVGALAEELGKEPSEIIKKLMLLGVMATINQELDKDTIELIASEYGVETEE
4               ------------------------------------------------------------
106             KIE-FTNSMTVGQLAEELGKETAEIIKKLMMLGVMATINQELDKDTVELIASEYGVPVEE
2               ------------------------------------------------------------
101             KVVKYEGSLTVGELAKKLSKEPSEIIKKLMMLGVMATINQDLDDDTIELIASEFGVEVQK
105             KVT-FVGSLTVSELAKELGKEPSEIIKKLFMLGVMATINQELDKDSIELIAGEYGVEVEE
103             KIT-FSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEE
102             KIT-YTTPITVGEFAEKINKEPSEVIKKLMFLGVMATINQELDKDAIELLSEDFGIEVEE
100             KIT-YSGSLTVGELAKLLHKEPSELIKKLMFLGVMSTINQELDKDTIELIAGDYGVEVEE
104             KIT-ISGSHTVSELAAKLHREASELIKKLIGLGVMATINQELDKDTIELLAADYGVEVEE
                                                                            

3               VIVLEETELEKYE-EPDNEEDLEIRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGIT
5               VIVLEETELEKYE-EPDNEEDLEIRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGIT
1               VIVLEETELEKYE-EPDNEEDLEIRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGIT
4               ------------------------------------------------------------
106             VIILEETELEKYE-VEDKEEDMQVRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGIT
2               ------------------------------------------------------------
101             EVVLDMTDLDSYI-VEDKPEELVERPPVVTIMGHVDHGKTTLLDSIRHAKVAAGEAGGIT
105             EVVVDDTAFESLE-IIDDEKDLQVRPPVVTIMGHVDHGKTTLLDSIRNTKVTAAEAGGIT
103             EVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGIT
102             EVVIDETEFENFE-ENDDPNELEERPPVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGIT
100             EIIIDEIDFEEYV-EVVNEENLAERPPVVTIMGHVDHGKTTLLDSIRQTKVTEGEAGGIT
104             EVIVDELDIELYD-REDKEEELKERPPVVTIMGHVDHGKTTLLDSIRNTKVTAGEAGGIT
                                                                            

3               QHIGAYQIEENGKKITFLDTPGHAAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINH
5               QHIGAYQIEENGKKITFLDTPGHAAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINH
1               QHIGAYQIEENGKKITFLDTPGHAAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINH
4               ------------------------------------------------------------
106             QHIGAYQIEENGKKITFLDTPGHAAFTMMRARGAEVTDTTILVVAADDGVMPQTVEAINH
2               ------------------------------------------------------------
101             QHIGAYQVEVNDKKITFLDTPGHEAFTTMRARGASVTDITILVVAADDGVMPQTKEAINH
105             QHIGAYQVVVDEKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTIEAINH
103             QHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINH
102             QHIGAYQVEENGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINH
100             QHIGAYQIETDGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTKEAISH
104             QHIGAYQIEHSGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTKEAISH
                                                                            

3               AKAAEVPIIVAVNKIDKESANPDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELV
5               AKAAEVPIIVAVNKIDKESANPDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELV
1               AKAAEVPIIVAVNKVDKESANPDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELV
4               ------------------------------------------------------------
106             AKAAEVPIIVAVNKIDKPTANPDRVMQELTEHGLVPEAWGGETIFVPLSAKTGEGIDELI
2               ------------------------------------------------------------
101             AKAAGVPIIVAVNKIDKESANPDRVMQELTEFNLIPESWGGDTIFVMLSALKGTGIDELL
105             AKAAEVPIIVAVNKMDKEAANPDRVMQELMEHGLVAEEWGGETIFCKLSAISGEGIDQLL
103             AKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLL
102             AKAAEVPIIVAVNKIDKEGANPDRVMQELTEHGLVSEAWGGETIFVHVSALNGTGIDELL
100             AKAAGVPIIVAVNKIDKEAANPDRVMQELTEFELVPEAWGGDTIFVNVSALSGTGIDELL
104             AKAAEVPIIVAVNKIDKETASPDRVMQELTEFELVPEAWGGDTIFVNVSALTGEGIDELI
                                                                            

3               EMILLVSEVEELKANPNRQAKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGR
5               EMILLVSEVEELKANPNRQAKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGR
1               EMILLVSEVEELKANPNRQAKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGR
4               ------------------------------------------------------------
106             EMILLVSEVGELKANPNRAAKGTVIEAELDKGRGSVATLLVQTGTLQVGDPIVVGNTFGR
2               ------------------------------------------------------------
101             EMILLVSEVEEYKANRERLAVGTVIEANLDKGRGPVATLLVQNGTLKVGDPIVVGSTYGR
105             EMILLVSEVEELKANPNRRAAGTVVEAQLDKGRGSVATLLVQTGTLRVGDPIVVGNTFGR
103             EMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGR
102             EMILLVSEVEELKANPNKLAKGTVVEAELDKGRGPVATLLVQAGTLRVGDPVVVGNTFGR
100             EMVLLVSEVAELKADPTLKAKGTVIEAELDKGRGAVATLLVQNGSLNVGDPIVVGSSFGR
104             EMILLVAEVEEFKANPDKLATGTVVEAQLDKGRGPVATLLVQSGTLNVGDAVVVGSTFGR
                                                                            

3               VRAMVNDIGRRVKTAGPSTPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQ
5               VRAMVNDIGRRVKTAGPSTPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQ
1               VRAMVNDIGRRVKTAGPSTPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQ
4               ------------------------------------------------------------
106             VRAMVNDIGRRVKTAGPSTPVEITGLNDVPNAGDQFLVFKDEKTARQVGEARASKQLDEQ
2               ------------------------------------------------------------
101             VRAMVNDLGRRVKVAPPSTPVEITGLHEVPSAGDRFIVFEDEKKARQVGEARAQKHIEEQ
105             VRAMVNDIGRRVKEVGPSTPVEITGLNEVPLAGDRFLVFEDEKTARQIGEARAQKQLEQQ
103             VRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQ
102             VRAMVNDIGRRVKAVGPSTPVEITGLNAVPQAGDQFVAFDDEKKSRQVGEARAVKQRESE
100             VRAMVNDLGRRVKRVGPSTPVEITGLNDVPLAGDQFQVFADEKKARQIGEARSSRQREEN
104             VRALVNDVGRRVKTAGPSAPVEITGLNEVPQAGDRFQAFEDEKKARQLGEGLMARYREQN
                                                                            

3               RSDKAKLSLDDLFEQIKQGDVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGV
5               RSDKAKLSLDDLFEQIKQGDVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGV
1               RSDKAKLSLDDLFEQIKQGDVKDINIIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGV
4               ------------------------------------------------------------
106             RSDKAKLSLDDLFEQIKQGEVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGV
2               ----------------------------------------------------MKIIHTGV
101             RTERNKVSLEDLFEQIKQGEMKEINLIVKADVHGSAEAMSSSLQKIDVEGVKVKIIHTGV
105             RGEKSRVSLDDLFEKIKQGEMKDLNLIVKADVQGSVEALAAALQKIDVEGVNVRIIHTGV
103             RGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGV
102             LRETSKVSLDDLFEQIQQGDIKEINVIVKADVQGSAEAMKGSLEKIEVEGVKVNIIHAGV
100             RSENSRVSLDDLFNQIQQGDVKDINIIIKADVQGSVEAMRGSLEKIDVAGVKVNIIHTGV
104             LTASSKVSLDDLFNQIQQGDVKDINVIIKADVQGSVEAMKGSLEKIDVAGVKVNIIHTGA
                                                                            

3               GAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGM
5               GAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGM
1               GAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGM
4               ----------------------MRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGM
106             GAITESDIILASASNAIVIGFNVRPDGNAKSTAETENVDIRLHRIIYKVIDEIEAAMKGM
2               GAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGM
101             GAITESDVILASASNAIIIGFNVRPDVNAKKTAEVENVDIRLHRIIYKAIEEIEAAMKGM
105             GAITESDIILATASNAIVIGFNVRPDAGAKRTADVENVDIRLHRIIYKVIEEIESAMKGM
103             GAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGM
102             GAIAESDIILASASNAIVIGFNVRPDVNAKRTAEQEKVDIRLHRVIYNAIDEVESAMKGM
100             GAITESDIILASASNAIVIGFSVRPDVNAKRVAESEKVDIRLHRVIYNAIDEIEAAMKGM
104             GAITESDIILASASNAIVIGFNVRPDVNAKRVAEAENVDIRLHRVIYNAIDEIEQAMKGA
                                      :*** .** .*: *:*******:**:.*:*:* **:* 

3               LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVL
5               LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVL
1               LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVL
4               LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVL
106             LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGIRLIRDGVVIFEGEVDVL
2               LDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVL
101             LDPEFEEKVIGQVEVRNTFKVSKVGTIAGCYVTDGKVTRDSGIRLVRDGVVIFEGEVDTL
105             LDPEFAEKIIGQVEVRQTFKVSKVGTIAGSYVTDGKITRNSGIRLIRDGIVIFEGEVDVL
103             LDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQLDTL
102             LDPEYEEKVIGQAEVRQTFKVSKIGTIAGSYVTDGKITRDSTVRLIRDGVVIFEGEINAL
100             LDPEFEEKVIGQVEIRTTFKVSKIGTIAGSYVTEGKISRDSTVRLIRDGVVIYEGAINAL
104             LDPEFEEKVIGQVEVRTTFKVSKVGTIAGSYVTEGKITRNSSVRLIRDGIVIYEGELNAL
                ****: **:***.*:* ****:*:***** ***:*.::*:* :*::***:**:** ::.*

3               KRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
5               KRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
1               KRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
4               KRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
106             KRFKDDVKEVSQGYECGITIKKYNDIREGDVLESFVMQEIERK
2               KRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
101             KRFKDDAKEVSQGYECGMTIKNFNDIKEGDIIEAYVMEEIERK
105             KRFKDDAKEVAQGYECGITIKNFNDIKEGDIIEAYVMEQIDPK
103             KRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR-
102             RRFKDDVKEVAQNYECGITLEKFNDVKEGDIIEAYVMEEIKR-
100             KRFKDDAKEVAAGYECGITLENFNDVKEGDIIEAYIMEEIERK
104             KRYKDDAKEVQAGYECGITLDKFNDIKEGDMIEAYVMEEVKRA
                :*:***.***  .****:*:..:**::***::*:::*:::.  
