CLUSTAL 2.1 multiple sequence alignment


4               ---MEKEA--FMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLI
5               ---MEKEA--FMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLI
2               ---MEKEA--FMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLI
1               ---MEKEA--FMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLI
3               ---MEKEA--FMDKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLI
104             ---MQKEE--FMNELLAFMKDEAYKPLTVQELEVMMEITNPDDYKELVKALVMLEDQGLI
103             ---MKEENQPYINEILDFMKRDNYKPLTVQELAKEFNTEDAESFKEFVKALVIMEEKGLI
101             ---MSEER---VERLLSFMREESYKPLTIKELEEVFGIEDSSDFKEFVKMLVQMEEQGLV
102             MEEIIQEH---IDKLLLFMREEAYKPLTIQELEEAFGIEGSEGFKDFVKALVTMEEKGLV
100             ---MNEEK---IQQLLRYFREDADKPLSVTELEEEFQIEGSEEFKEFVKGLNELEAKGHI
                   : :*    ::.:* ::: :  ***:: **   :    .. :*::** *  :* :* :

4               VRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDT--SLSDVFIPPNELNTAMNGDIVM
5               VRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDT--SLSDVFIPPNELNTAMNGDIVM
2               VRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDT--SLSDVFIPPNELNTAMNGDIVM
1               VRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDT--SLSDVFIPPNELNTAMNGDIVM
3               VRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDT--SLSDVFIPPNELNTAMNGDIVM
104             VRTRSDRYGVPEKMNLVKGKLSAHAKGFAFVTPEEF--GQDDIFIPPNELGTAMNGDTVM
103             IRARNDRYGLPEQMNFVKGKVSGHAKGFAFVVPEEK--DAGDVFIPPTETNNAMHGDIVL
101             VRTRSNRYGVPERMNMVKGRVIAHSKGFAFVEQEDK--SLDDIFIPPSEMRSAMHGDIVL
102             IRTRSNRYGLPEKMNLVRGKLIGHARGFAFVVPDEKKTGDDDLFIPPTELNGALHGDTVL
100             VRTRSDRYGVPEKMNLVRGRVQGHAKGFAFIIPEVE--GEKDVYVSQSDLKSAMNGDTVL
                :*:*.:***:**:**:::*:: .*::****:  :    .  *:::. .:   *::** *:

4               VRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNG
5               VRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNG
2               VRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNG
1               VRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNG
3               VRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNG
104             VRVSHKSNGTKKEGTVIRILERNTQTVVGTYTETKSFGFVIPDDKKITTDIFIPKSAKNG
103             ARVSSESSGARREGTIVKILERGTQQIVGTYTQSKNFGFVIADDKKIAGDIFIPKAARNG
101             ARIDKHPADGRPEGAIVRVIERGVTQIVGTYVDNKYFGFVIPDDKRIGSDIFIAKEAKNG
102             ARLSSQSSGSRQEGSIVRILERGTKELVGTYTESKNFGFVIPDNKRWTSDIFVLKSASMG
100             VRLHQESSGARPEGKVIRILERGVQEVVGTYSDQKAYGFVVADDKRIANDIFIPKNAING
                .*:  .. . : ** :::::**    :**** : : :***:.*:*:   ***: * .  *

4               AAEGHKVVVKLTSYPEGRMNAEGEVETILGHKNDPGIDILSVIHKHGLPGEFPADAMEQA
5               AAEGHKVVVKLTSYPEGRMNAEGEVETILGHKNDPGIDILSVIHKHGLPGEFPADAMEQA
2               AAEGHKVVVKLTSYPEGRMNAEGEVETILGHKNDPGIDILSVIHKHGLPGEFPADAMEQA
1               AAEGHKVVVKLTSYPEGRMNAEGEIETILGHKNDPGIDILSVIHKHGLPGEFPADAMEQA
3               AAEGHKVVVKLTSYPEGRMNAEGEIETILGHKNDPGIDILSVIHKHGLPGDFPADAMEQA
104             AVEGHKVVVTLTSYPEGRMSAEGEVTEILGHKNDPGIDILSIIHKHGLPGEFPEEALQQA
103             AVEGHKVVVELTTYPEGRMNAEGKVVQILGHKNDPGIDIISVIHKHGLPQEFPADALTQA
101             AVEGHKVVVKLIKYPEGRMNAEGEITEILGHKNDPGVDILSIIHKHQLPGDFPPDVMEQA
102             AVEGHKVVVKITSYPENRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHA
100             AVDGHKVIVKIVKYPEGRMSAEGEVVRILGHKNDPGMDILSIIYKHGIPLEFSDDVMEQA
                *.:****:* : .***.*:.***::  *********:**:*:*:** :*  *. :.: :*

4               SSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHY
5               SSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHY
2               SSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLEDGSYKLGVHIADVSHY
1               SSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHY
3               SSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHY
104             VDTPETIDEKDLEGRRDLRNETIVTIDGADAKDLDDAVTVQKLDDGKYKLGVHIADVSHY
103             IDTPETIDEKDIGNRRDLRDQVIVTIDGADAKDLDDAVTVTELENGNYKLGVHIADVSHY
101             HNTPDEINPDELTNRRDLRDQTIVTIDGADAKDLDDAVTVTKLDNGNYKLGVHIADVSYY
102             NSVPETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHY
100             NNVSEQIDEQDLEGRRDLRDEVIVTIDGADAKDLDDAVHVKKLENGNYLLGVHIADVSHY
                 ...: *. .:: .*****:: **************** * :*::*.* *********:*

4               VTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQV
5               VTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQV
2               VTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQV
1               VTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQV
3               VTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQV
104             VTENSPIDQEAYERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMVIDRNGKV
103             VKEGSPIDVEAAERGTSVYLVDRVIPMIPHRLSNGICSLNPKVNRFTLSCEMEIDPQGEV
101             VTEGSAIDKEAFNRGTSIYLVDRVIPMIPHRLSNGICSLNPQVDRLTMSCEMEINSNGEV
102             VQEGSPIDVEAAERATSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEINNLGDV
100             VTEGSPIDKEAADRATSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEINSAGEV
                * *.*.** ** :*.**:***********************:*:*:*:**** *:  *.*

4               TEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERLAQILRDKRMDR
5               TEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERLAQILRDKRMDR
2               TEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERLAQILRDKRMDR
1               TEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLIPMFKDMERLAQILRDKRMNR
3               TEHEIFQSVIKTTERMTYSDVNQILVDDDEELKQKYEPLVPMFKDMERLAQILRDKRMNR
104             VKHEIFQSVIKTTERMTYTDVNKILVDQDEELIDKYELLVPMFQEMEKLAEILRDKRMER
103             VKHEIFESVIKTTERMTYSDVNKILVDKDEEVLERYEPIVPMFERMEKLAAILRKKRMDR
101             VSHEIFQSVIKTTERMTYSDVNKIIDDKDPELLEKYKPLVPMFLLMDELAEILRKKRFER
102             VKHEIFQSVIKTTERMTYADVRSILEDEDEELIKRYEPLVPMFKEMGQLAQILREKRMRR
100             VKHEIFQSVIKTTERMTYSDVNKILVDGDTEVKEKYEQLVPLFQEMEKLAQTLRTKRFDR
                ..****:***********:**..*: * * *: .:*: ::*:*  * .**  ** **: *

4               GAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYR
5               GAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYR
2               GAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYR
1               GAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYR
3               GAVDFDFKEAKVLVDEEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYR
104             GAVDFDFKEAKVLVDDEGAAKDVVVRERSVAEKLIEEFMLVANETVAEHFHWLNVPFIYR
103             GAIDFDFKEAKVLVDDDGHPHDVILRERSVAEKLIEEFMLAANETVAEHFHWMNVPFIYR
101             GAIDFDFKEAKVLVDEYGKPTDVIIRERSSGERLIEDFMLIANETVAEHFHWMNLPFIYR
102             GAIDFDFKEAKVLVDEEGKPTDVVMRDRSVSEKLIEEFMLVANETVAEHFHWMNVPFMYR
100             GAIDFDFKEAKVLVDEEGKAQEVVLRERSVAEKLIEEFMLAANETVAEHFHWLKLPFVYR
                **:************: *   :*::*:** .*:***:*** ***********:::**:**

4               IHEEPNAEKLQKFLEFVTTFGYVVKGTAGNIHPRALQSILDAVRDRPEETVISTVMLRSM
5               IHEEPNAEKLQKFLEFVTTFGYVVKGTAGNIHPRALQSILDAVRDRPEETVISTVMLRSM
2               IHEEPNAEKLQKFLEFVTTFGYVVKGTAGNIHPRALQSILDAVRDRPEETVISTVMLRSM
1               IHEEPNAEKLQKFLEFVTTFGYVVKGTAGDIHPRALQSILDAVRDRPEETVISTVMLRSM
3               IHEEPNAEKLQKFLEFVTTFGYVVKGTAGDIHPRALQSILDAVRDRPEETVISTVMLRSM
104             IHEEPNPEKLQRFLEFVTTFGYIVKGTSTNIHPRALQSVLDAVRDQPEEVVIQTVMLRSM
103             IHEDPDAEKLTRFLEFITNFGYTVKGTGNDIHPRALQDILEEVKGTPEEMVISTVMLRSM
101             VHEDPKEEKLSRFFEFITNFGYVVKGTANDVHPRALQQILEEVRGTPEEMVISTVMLRSM
102             VHEDPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEVVISTVMLRSM
100             IHEDPDAEKLNKFLEFITNFGYVVRGNANTVHPRALQKLLDEVRGEPEETVISTVMLRSM
                :**:*. :** :*:**:*.*** *:* .  :******.:*: *:. *** **.*******

4               KQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERL
5               KQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERL
2               KQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERL
1               KQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERL
3               KQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERL
104             KQAKYDPESIGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLIQKKTDEATLEKWGQLL
103             KQAKYEAESLGHFGLSAEFYTHFTSPIRRYPDLIVHRLIRTYLIEGKTDQQTQEKWRELL
101             KQARYDAESLGHFGLSAEFYTHFTSPIRRYPDLIVHRLIRTYLIEGKIDEQTQSLWRAEL
102             KQARYDAESLGHFGLSTEFYTHFTSPIRRYPDTIVHRLIREYIINGKVDNETQAKWREKL
100             QQAKYDTNSLGHFGLSTDFYTHFTSPIRRYPDLLVHRLIRTYLIRGNVDQETQSHWAEKL
                :**:*:.:*:******::************** :****** *:*. : *: *   *   *

4               PDIAEHTSSMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIEG
5               PDIAEHTSSMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIEG
2               PDIAEHTSSMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIEG
1               PDIAEHTSTMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIEG
3               PDIAEHTSTMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIEG
104             PEIADHASTMERRSVDAERETDDLKKAEFMLDKIGEEFDGMISSVTNFGLFVELPNTIEG
103             PDVAEHSSNMERRSVDAERETDDMKKAEFMADKVGEVFNGIISSVTNFGMFVELENTIEG
101             PDIAEHTSNMERRAVDAERETDDLKKAEFMLDKIGEEFDGIISSVTNFGFFVELPNTVEG
102             PEIAEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMISSVTNFGLFVELPNTIEG
100             PELTRHSSEMERRAVDAERDTDSVKKAQFMEDKIGEVFTGMISGVTNFGLFVELENTIEG
                *::: *:* ****:*:***:**.:***::* **:** : *:**.*****:**** **:**

4               LVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGT
5               LVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGT
2               LVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGT
1               LVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGS
3               LVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGS
104             LVHVSYMTDDYYRFDEQHFAMIGERTGNVYRIGDEITVKVVNVNKDEHSIDFEIVGMKGT
103             LVHVSDLTDDYYRYDERHYAMIGEKTGNVFRIGDEIEVKVADVNKDERSVDFIIVGMKES
101             LVHVSYLTDDYYRYDETSYAMIGERTGNIFRIGDEITVRVVNVDKDERIVDFEIVGMKGT
102             LVHVSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGT
100             LVHVSYLTDDYYHYDEKQYAMIGERSGQVFRIGDEIEVRVVNVNVEEASIDFEVVGMKPR
                ***** :*****::**  :*****::*:::****** ::* :*: :*  :** :****  

4               PRRPRELDSSRSRK---------------------RGKPARKRVQSTNTPVSPAP-----
5               PRRPRELDSSRSRK---------------------RGKPARKRVQSTNTPVSPAP-----
2               PRRPRELDSSRSRK---------------------RGKPARKRVQSTNTPVSPAP-----
1               PRRPRELDSSRSRK---------------------RGKPARKRVQSTNTPVSPAP-----
3               PRRPRELDSSRSRK---------------------RGKPARKRVQSTNTPVSPAP-----
104             -RRKSPKDFKFKKR---------------------TDSPAKKGHGSQNASGDKAK-----
103             RKRLS-KDRPKVIK---------------------AKQKSRKDDKGKGREGSRSK-----
101             RRTERRQTPKVFQS--------GGRG---------RGSGRDQSSGGKSNSRSQGKQGSGS
102             PRRKFKDRPVVIEQPRTGRKKRGGRSERSNERGGERGTGRKFDRGGKGKGTGKGRGSTSA
100             KRRERPSRPTVIEGGKRKKRQ-------------GGRGGQGDSNGGRGQTGNKKQGLSLG
                 :                                           . .   .        

4               SEEKG-EWFTKPKKKKKKRGFQNAPKQKRKKKK----
5               SEEKG-EWFTKPKKKKKKRGFQNAPKQKRKKKK----
2               SEEKG-EWFTKPKKKKKKRGFQNAPKQKRKKKK----
1               SEEKG-EWFTKPKKKKKKRGFQNAPKQKRKKKK----
3               SEEKG-EWFTKPKKKKKKRGFQNAPKQKRKKKK----
104             EDKGGSDWFTGRKKKKKKRVFDNAPKQKRKKKK----
103             NEEWS---TQKPKKKKKKRFFEGAPNVKRKKKKRK--
101             NRNA----KKDHKNKDGQPYYRNVA--KKKKKKRK--
102             SASASQPGKKEGNGKKKKAFFENVPGFKKKKKKRK--
100             DKPNG--SGSGRKKKKKKGFYENAPAVKRKKGRKKKK
                .           : *. :  : ...  *:** :    
