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Algorithmic development of translatable CT-based biomarkers for disease phenotyping and prediction of therapeutic response and survival.


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Disease Progression Modeling in Chronic Obstructive Pulmonary Disease

Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study

Multicenter evaluation of parametric response mapping as an indicator of bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation

Lung T1 mapping magnetic resonance imaging in the assessment of pulmonary disease in children with cystic fibrosis: a pilot study

Gene expression profiling of bronchial brushes is associated with the level of emphysema measured by computed tomography-based parametric response mapping


Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease

Imaging Advances in Chronic Obstructive Pulmonary Disease. Insights from the Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) Study

Relationship between diffusion capacity and small airway abnormality in COPDGene

Functional CT imaging for identification of the spatial determinants of small-airways disease in adults with asthma

Assessing small airways dysfunction in asthma, asthma remission and healthy controls using particles in exhaled air

Comparison of Voxel-Wise and Histogram Analyses of Glioma ADC Maps for Prediction of Early Therapeutic Change


Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials

Influence of Inspiratory/Expiratory CT Registration on Quantitative Air Trapping

Voxel-Wise Longitudinal Parametric Response Mapping Analysis of Chest Computed Tomography in Smokers

Convolutional Neural Network Based COPD and Emphysema Classifications Are Predictive of Lung Cancer Diagnosis

Validation of automated lobe segmentation on paired inspiratory-expiratory chest CT in 8-14 year-old children with cystic fibrosis


CT-Based Local Distribution Metric Improves Characterization of COPD

The role of chest computed tomography in the evaluation and management of the patient with chronic obstructive pulmonary disease

A bifunctional MAPK/PI3K antagonist for inhibition of tumor growth and metastasis

Parametric response mapping as an imaging biomarker in lung transplant recipients

Small airway imaging phenotypes in biomass- and tobacco smoke-exposed patients with COPD

Diffusion MRI in early cancer therapeutic response assessment

Age and small airway imaging abnormalities in subjects with and without airflow obstruction in spiromics

Parametric response mapping on chest computed tomography associates with clinical and functional parameters in chronic obstructive pulmonary disease

Fully automated lobe-based airway taper index calculation in a low dose MDCT CF study over 4 time-points


Parametric Response Mapping of Bronchiolitis Obliterans Syndrome Progression After Lung Transplantation

Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease

Evaluation of Concurrent Radiation, Temozolomide and ABT-888 Treatment Followed by Maintenance Therapy with Temozolomide and ABT-888 in a Genetically Engineered Glioblastoma Mouse Model


Effects of ageing and smoking on pulmonary computed tomography scans using parametric response mapping

Integrated Multimodal Imaging of Dynamic Bone-Tumor Alterations Associated with Metastatic Prostate Cancer

Multi-Site Clinical Evaluation of DW-MRI as a Treatment Response Metric for Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer

Feasibility Analysis of the Parametric Response Map as an Early Predictor of Treatment Efficacy in Head and Neck Cancer

Parametric Response Mapping Monitors Temporal Changes on Lung CT Scans in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Erratum for the Research Article: “Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer”


Image Registration for Quantitative Parametric Response Mapping of Cancer Treatment Respons

A Pilot Study of Diffusion-Weighted MRI in Patients Undergoing Neoadjuvant Chemoradiation for Pancreatic Cancer

Correlation of thrombus formation on 7 T MRI with histology in a rat carotid artery side wall aneurysm model


Imaging Proteolytic Activity in Live Cells and Animal Models

Multi‐system repeatability and reproducibility of apparent diffusion coefficient measurement using an ice‐water phantom

Impact of Perfusion Map Analysis on Early Survival Prediction Accuracy in Glioma Patients

Diffusion-Weighted MRI as a Biomarker of Tumor Radiation Treatment Response Heterogeneity: A Comparative Study of Whole-Volume Histogram Analysis versus Voxel-Based Functional Diffusion Map Analysis

Molecular Imaging Reveals a Role for AKT in Resistance to Cisplatin for Ovarian Endometrioid Adenocarcinoma

DW-MRI as a Predictive Biomarker of Radiosensitization of GBM through Targeted Inhibition of Checkpoint Kinases


Metastatic Pancreatic Cancer Is Dependent on Oncogenic Kras in Mice

Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression

DCE and DW‐MRI monitoring of vascular disruption following VEGF‐Trap treatment of a rat glioma model

Parametric response mapping of CT images provides early detection of local bone loss in a rat model of osteoporosis

Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cance

DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

Predicting treatment efficacy via quantitative magnetic resonance imaging: a Bayesian joint model

Multimodal Imaging of Growth and Rapamycin-Induced Regression of Colonic Adenomas in Apc Mutation-Dependent Mouse

Multimodality Imaging of Tumor and Bone Response in a Mouse Model of Bony Metastasis


Diffusion coefficient measurement using a temperature‐controlled fluid for quality control in multicenter studies

Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles

Prospective Analysis of Parametric Response Map–Derived MRI Biomarkers: Identification of Early and Distinct Glioma Response Patterns Not Predicted by Standard Radiographic Assessment

Molecular imaging of c-Met tyrosine kinase activity

Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting

Perifosine and CCI 779 Co-Operate to Induce Cell Death and Decrease Proliferation in PTEN-Intact and PTEN-Deficient PDGF-Driven Murine Glioblastoma


Superparamagnetic Iron Oxide Nanotheranostics for Targeted Cancer Cell Imaging and pH-Dependent Intracellular Drug Release

Applications of Molecular Imaging

Assessment of multiexponential diffusion features as MRI cancer therapy response metrics

Reply to S. Heiland et al

Diffusion-Weighted MRI for Assessment of Early Cancer Treatment Response

Parametric Response Map As an Imaging Biomarker to Distinguish Progression From Pseudoprogression in High-Grade Glioma

Utility of the K-Means Clustering Algorithm in Differentiating Apparent Diffusion Coefficient Values of Benign and Malignant Neck Pathologies

valuation of Treatment-Associated Inflammatory Response on Diffusion-Weighted Magnetic Resonance Imaging and 2-[18F]-Fluoro-2-Deoxy-d-Glucose-Positron Emission Tomography Imaging Biomarkers

Comparison of apparent diffusion coefficients and distributed diffusion coefficients in high‐grade gliomas

Intravoxel water diffusion heterogeneity imaging of human high‐grade gliomas


Advanced MRI: Translation from Animal to Human in Brain Tumor Research

Voxel-by-Voxel Functional Diffusion Mapping for Early Evaluation of Breast Cancer Treatment

Axin expression in thymic stromal cells contributes to an age‐related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling

The parametric response map is an imaging biomarker for early cancer treatment outcome

Synergy between anti‐CCL2 and docetaxel as determined by DW‐MRI in a metastatic bone cancer model

A Feasibility Study of Parametric Response Map Analysis of Diffusion-Weighted Magnetic Resonance Imaging Scans of Head and Neck Cancer Patients for Providing Early Detection of Therapeutic Efficacy