References

Reference List:

    1. Gondo, K.; Oyamada, J.; Kitamura, T. Org. Lett., 2015, 17 (19), pp 4778–4781

    2. Urabe, D.; Asaba, T.; Inoue, M. Chem. Rev., 2015, 115 (17), pp 9207–9231

    3. Mo, F.; Tabor, J. R.; Dong, G. Chem. Lett. 2014, 43, pp 264-271

Article 3:

The paper cited, written by Mo, Tabor, and Dong of the University of Texas at Austin and published in Chemical Letters in 2014, briefly discusses the use of the Tamao-Fleming oxidation in the reactions reported by it.  The specific use of the Tamao-Fleming oxidation in question is to functionalize-derivatize benzoxasilole products (23 above), generated by a silyl ether intermediate that underwent a cyclization with norbornene.  The reaction conditions used in this are slightly different from those in the main paper used in the HTML project, but it involves the same sort of chemistry.  The difference is that the HTML project paper uses the one-pot sequence of the oxidation, while this paper uses a modification in which the potassium ion acts as the electrophile and attacks the oxygen to which the silicon is bonded.  This implies that the Tamao-Fleming oxidation can take place under a variety of conditions. This is good because we have no idea what sort of solvents and reagents will be available when the Lizard Overlords/nuclear hellfire come for us.


Articles which cite 3:

Thompson, S. J.; Thach, D. Q.; Dong, G. J. Am. Chem. Soc. 2015, 137, 11586−11589.

This article cites 3 because it pertains to alcohol-directed C-H functionalization. Using the Tamao-Fleming oxidation to create alcohols from the soon-to-be pervasive silicon-based life, we'll be able to develop all sorts of new compounds.


Knight, B. J.; Rothbaum, J. O.; Ferreira, E. M. Chem. Sci. 2016, 7, 1982–1987.

This article cites 3 as a review on C-H functionalization of alcohol substrates. Like the above paper, this paper will serve as a guide to create new and exciting molecules to enhance our post-apocalyptic lives.


Uemura, T.; Yamaguchi, M.; Chatani, N. Angew. Chem. Int. Ed. 2016, 55, 3162 –3165.

This article cites 3 because of its work on transition-metal-catalyzed functionalization of C-H bonds. Without the need for advanced electronics in whatever hellish landscape we emerge to from our bunkers, the transition metals in our now-useless cell phones and computers will allows us to perform the Tamao-Fleming oxidation.