FCHSD2

General Information

Full gene name:FCH and double SH3 domains 2 Entrez Gene ID:9873 Location:11q13.4 Synonyms:SH3MD3, NWK Type:protein-coding

User SNPs

SNPs given by the user that are near or inside this gene:

SNP	Distance (bp)	Direction
rs1552224	114692	downstream

NCBI Summary

None available.

OMIM

No OMIM data available for this gene.

NCBI Phenotypes

No phenotypes found linked to this gene.

Gene Ontology

• protein binding

KEGG Pathways

No pathways found linked to this gene.

GeneRIFs

• Affinity Capture-Western; Reconstituted Complex; Two-hybrid [PMID 14627983]
• Reconstituted Complex [PMID 14627983]
• Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) [PMID 20379614]
• Two-hybrid [PMID 22558309]
• Two-hybrid [PMID 22558309]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Affinity Capture-Western; Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 18654987]
• Two-hybrid [PMID 16189514]
• Two-hybrid [PMID 16189514]

PubMed Articles

Recent articles:

• Wong KA et al. “Intersectin (ITSN) family of scaffolds function as molecular Hubs in protein interaction networks.” PLoS One. 2012;7(4):e36023. PMID 22558309
• Rose JE et al. “Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.” Mol Med. 2010 Jul-Aug;16(7-8):247-53. PMID 20379614
• Thalappilly S et al. “Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.” Proteomics. 2008 Aug;8(15):3071-81. PMID 18654987
• Taylor TD et al. “Human chromosome 11 DNA sequence and analysis including novel gene identification.” Nature. 2006 Mar 23;440(7083):497-500. PMID 16554811
• Rual JF et al. “Towards a proteome-scale map of the human protein-protein interaction network.” Nature. 2005 Oct 20;437(7062):1173-8. PMID 16189514
• Gerhard DS et al. “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” Genome Res. 2004 Oct;14(10B):2121-7. PMID 15489334
• Murwantoko et al. “Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease.” Biochem J. 2004 Aug 1;381(Pt 3):895-904. PMID 15101818
• Katoh M et al. “Identification and characterization of human FCHSD1 and FCHSD2 genes in silico.” Int J Mol Med. 2004 May;13(5):749-54. PMID 15067381
• Coyle IP et al. “Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila.” Neuron. 2004 Feb 19;41(4):521-34. PMID 14980202
• Ohno H et al. “Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.” Oncogene. 2003 Nov 20;22(52):8422-31. PMID 14627983