SRPK3
SNPs given by the user that are near or inside this gene:
| SNP |
Distance (bp) |
Direction |
|---|
| rs3020789 |
153469 |
upstream |
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
No OMIM data available for this gene.
No phenotypes found linked to this gene.
- protein phosphorylation
- cellular_component
- cell differentiation
- muscle tissue development
- ATP binding
- skeletal muscle tissue development
- protein serine/threonine kinase activity
No pathways found linked to this gene.
Recent articles:
- Danielsen JM et al. “Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.” Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. PMID 21139048
- Nakagawa O et al. “Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.” Genes Dev. 2005 Sep 1;19(17):2066-77. PMID 16140986
- Li J et al. “Regulation of alternative splicing by SRrp86 and its interacting proteins.” Mol Cell Biol. 2003 Nov;23(21):7437-47. PMID 14559993
- Strausberg RL et al. “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.” Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. PMID 12477932
- Grunau C et al. “Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes.” Hum Mol Genet. 2000 Nov 1;9(18):2651-63. PMID 11063724