Total Synthesis of (-)-Morphine3
Koizumi, H.; Yokoshima, S.; Fukuyama, T. Chem. Asian J. 2010, 5, 2192-2198.
Alcohol 22 was oxidized to ketone 23 using Dess-Martin periodinane. These are key intermediates in a relatively more efficient synthesis of (-)-morphine, which can help lead to the synthesis of non-addictive morphine analogues.
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