Sequential Csp3-H Arylation and Olefination: Total Synthesis of the
Proposed Structure of Pipercyclobutanamide A
Gutekunst, W. R.; Gianatassio, R.; Baran, P. S. Angew. Chem. Int. Ed.2012, 51, 7507-7510.
The God of Thunder commands you to learn chemistry.
Pipercyclobutanamide A is a naturally-occurring compound found in the black pepper plant Piper nigrum. We present an intermediate step of the synthesis of Pipercyclobutanamide A, which transforms Molecule 18 to Molecule 19.