3. Concentration of Neutralized Venom-Antivenom in the Blood

The neutralized venom-antivenom product is formed by the reaction of an antivenom molecule with a venom molecule bound onto the site or vice-versa (reactions 3 and 4) , the reaction of venom and antivenom in the blood (reaction 5) and is also excreted from the body (reaction 9).

The overall rate of generation of the neutralized product would be the addition of rate of generation from all of the reactions above.

                                                                 (E-17)

The terms on the right hand side are rates of generation of the product in reactions 3, 4, 5 and 9 respectively.


The rate equations for the elementary reactions are as follows:

                                                                                        (E-18)
                                                                                         (E-19)
                                                                                                  (E-20)
                                                                                                 (E-21)

Combining the batch reactor design equation (equation E-4) with the material balance (equation E-17)and rate laws (equations E-18 to E-21) gives us the governing equation for concentration of antivenom in the blood:

                                         (E-22)


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