66 |
"Robotically assisted titration coupled to ion mobility-mass spectrometry reveals the interface structures and analysis parameters critical for multiprotein topology mapping" Yueyang Zhong, Jun Feng, Brandon T. Ruotolo.
Anal Chem. (2013), doi: 85(23):11360-8
Link
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65 |
"Ion mobility-mass spectrometry of intact protein-ligand complexes for pharmaceutical drug discovery and development" Shuai Niu, Jessica N. Rabuck, Brandon T. Ruotolo.
Current Opinion in Chemical Biology (2013), doi:10.1016/j.cbpa.2013.06.019
Link
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64 |
"An Activation State-Selective Kinase Inhibitor Assay Based on Ion Mobility-Mass Spectrometry." Jessica N. Rabuck, Suk-Joon Hyung, Kristin S. Ko, Christel C. Fox, Matthew B. Soellner, Brandon T. Ruotolo.
Anal. Chem. (2013), doi:10.1021/ac4012655
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63 |
"Hofmeister Salts Recover a Misfolded Multiprotein Complex for Subsequent Structural Measurements in the Gas Phase" Linjie Han, Brandon T. Ruotolo.
Angew. Chem. Int. Ed. (2013), doi: 10.1002/anie.201301893
Link
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62 |
"Analysis of a Soluble (UreD:UreF:UreG)2 Accessory Protein Complex and Its Interactions with Klebsiella aerogenes Urease by Mass Spectrometry" Mark A. Farrugia, Linjie Han, Yueyang Zhong, Jodi L. Boer, Brandon T. Ruotolo, Robert P. Hausinger.
Journal of The American Society for Mass Spectrometry (2013), doi:10.1007/s13361-013-0677-y
Link
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61 |
"Amyloid-b-neuropeptide interactions assessed by ion mobility-mass spectrometry" Molly T. Soper, Alaina S. DeToma, Suk-Joon Hyung, Mi Hee Lim, Brandon T. Ruotolo.
Phys. Chem. Chem. Phys.(2013), doi: 10.1039/C3CP50721A
Link
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60 |
"Traveling-wave ion mobility-mass spectrometry reveals additional mechanistic details in the stabilization of protein complex ions through tuned salt additives" Linjie Han,
Brandon T. Ruotolo.
International Journal for Ion Mobility Spectrometry. (2013), doi: 10.1007/s12127-013-0121-9
Link
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59 |
"Resolution of Oligomeric Species during the Aggregation of Ab1-40 Using 19F NMR." Yuta Suzuki, Jeffrey R. Brender, Molly T. Soper, Janarthanan Krishnamoorthy, Yunlong Zhou, Brandon T. Ruotolo, Nicholas A. Kotov, Ayyalusamy Ramamoorthy, E Neil G. Marsh.
Biochemistry (2013), doi:10.1021/bi400027y
Link
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58 |
"Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-beta species" Suk-Joon Hyung, Alaina S. DeToma, Jeffrey R. Brender, Sanghyun Lee, Subramanian Vivekanandan, Akiko Kochi, Jung-Suk Choi, Ayyalusamy Ramamoorthy, Brandon T. Ruotolo, and Mi Hee Lim.
Proc. Natl. Acad. Sci. (2013), doi: 10.1073/pnas.1220326110
Link
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57 |
"Dramatically stabilizing multiprotein complex structure in the
absence of bulk water using tuned Hofmeister salts" Linjie Han,
Suk-Joon Hyung, Brandon T. Ruotolo.
Faraday Discuss. (2013)160, 371-388
Link
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56 |
"Bound cations significantly stabilize the structure of multiprotein
complexes in the gas phase" Linjie Han, Suk-Joon Hyung, Brandon T.
Ruotolo.
Angew. Chem. Int. Ed. (2012)51, 5692-5695.
Link
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55 |
"Investigation of Flavonoid Compounds as Modulators for Metal-Associated Amyloid-b Species" Xiaoming He, Hyun Min Park, Suk-Joon Hyung, Alaina S. DeToma, Cheal Kim, Brandon T. Ruotolo, Mi Hee Lim Dalton Trans. (2012) 41, 6558-6566.
Link
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54 |
"Reactivity of Diphenylpropynone Derivatives Toward Metal-Associated Amyloid-b Species" Amit S. Pithadia, Akiko Kochi, Molly T. Soper, Michael W. Beck, Yuzhong Liu, Sanghyun Lee, Alaina S. Detoma, Brandon T. Ruotolo, Mi Hee Lim.
Inorg. Chem. (2012)51, 12959-12967
Link
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53 |
"Integrating mass spectrometry of intact protein complexes into structural proteomics"
Suk-Joon Hyung, Brandon T. Ruotolo.
Proteomics. (2012)12, 1547-64
Link
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52 |
"Ion mobility-mass spectrometry for structural proteomics"
Yueyang Zhong, Suk-Joon Hyung, Brandon T. Ruotolo.
Expert Rev. Proteomics (2012)9, 47-58
Link
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51 |
"Gas-Phase Protein Assemblies: Unfolding Landscapes and Preserving Native-Like Structures using Noncovalent Adducts"
Joanna Freeke, Matthew F Bush, Carol V Robinson*, Brandon T. Ruotolo* (joint corresponding authors)
Chem. Phys. Lett.(2012)524, 1-9
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50 |
"Mass spectrometry: come of age for structural and dynamical biology"
Justin LP Benesch, Brandon T Ruotolo.
Curr Opin Struct Biol. (2011)21, 641-9
Link
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49 |
"Ion Mobility-Mass Spectrometry Reveals Conformational Changes in Charge Reduced Multiprotein Complexes"
Russell E. Bornschein, Suk-Joon Hyung and Brandon T. Ruotolo
J. Am. Soc. Mass. Spectrom. (2011)22, 1690-8
Link
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48 |
"Bound Anions Differentially Stabilize Multiprotein Complexes in the Absence of Bulk Solvent"
Linjie Han, Suk-Joon Hyung, Jonathan J. S. Mayers, Brandon T. Ruotolo.
J. Am. Chem. Soc. (2011)133,11358-67
Link
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47 |
"A Two-Site Mechanism for the Inhibition of IAPP Amyloidogenesis by Zinc " Samer Salamekh, Jeffrey R. Brender, Suk-Joon Hyung, Ravi Prakash Reddy Nanga, Subramanian Vivekanandan, Brandon T. Ruotolo, Ayyalusamy Ramamoorthy.
J. Mol. Biol. (2011)410,294-306
Link
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46 |
"Tandem Differential Mobility Analysis-Mass Spectrometry Reveals Partial Gas-Phase Collapse of the GroEL Complex." Christopher J. Hogan Jr, Brandon T. Ruotolo, Carol V. Robinson, Fernandez de la Mora J
J. Phys. Chem. B (2011)115, 3614-21
Link
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45 |
"Characterizing the resolution and accuracy of a second-generation traveling-wave ion mobility separator for biomolecular ions." Yueyang Zhong, Suk-Joon Hyung, Brandon T. ; Ruotolo
Analyst (2011)136, 3534-41
Link
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44 |
"Ion mobility-mass spectrometry reveals the influence of subunit packing and charge on the dissociation of multiprotein complexes." Elisabetta Boeri Erba, Brandon T. Ruotolo, Daniel Barsky, Carol V. Robinson
Anal. Chem. (2010) 82, 9702-10.
Link
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43 |
"Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology." Matthew F. Bush, Zoe Hall, Kevin Giles, John Hoyes, Carol V. Robinson, Brandon T. Ruotolo
Anal. Chem. (2010) 82, 9557-65.
Link
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42 |
"Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes." Argyris Politis, Ah Young Park, Suk-Joon Hyung, Daniel Barsky, Brandon T. Ruotolo, Carol V. Robinson
PLoS One (2010) 10, e12080.
Link
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41 |
"Alternate dissociation pathways identified in charge-reduced protein complex ions." Kevin Pagel, Suk-Joon Hyung, Brandon T. Ruotolo, Carol V. Robinson
Anal. Chem. (2010) 18, 5363-72.
Link
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40 |
“A Single Subunit Directs the Assembly of the E. coli DNA Sliding Clamp Loader” Ah Young Park, Slobodan Jergic, Argyris Politis, Brandon T. Ruotolo, Daniel Hirshberg, Linda L. Jessop, Jennifer L. Beck, Daniel Barsky, Mike O’Donnell, Nichlas E. Dixon, Carol V. Robinson
Structure (2010) 18, 285-292.
Link
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39 |
“Separating and visualising protein assemblies by means of preparative mass spectrometry and microscopy” Justin L.P. Benesch, Brandon T. Ruotolo, Douglas A. Simmons, Nelson P. Barrera, Nina Morgner, Luchun Wang, Helen R. Sabil, Carol V. Robinson
J. Struct. Biol. (2010)
Link
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38 |
“Methodology for Measuring Conformation of Solvent-disrupted Protein Subunits using T-wave Ion Mobility MS: An investigation into Eukaryotic Initiation Factors” Julie A. Leary, Matthew R. Schenauer, Raluca Stefanescu, Armann Andaya, Brandon T. Ruotolo, Carol V. Robinson, Kostos Thallasinos, James Scrivens, Masaaki Sokabe, John F. Hershey
J. Am. Soc. Mass Spectrom. (2009) 20, 1699-1706.
Link
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37 |
“Subunit Architecture of Multi-protein Assemblies Determined using Restraints from Gas-phase Measurements” Tara L. Pukala, Brandon T. Ruotolo, Min Zhou, Argyris K. Politis, Raluca Stefanescu, Julie A. Leary, Carol V. Robinson
Structure (2009) 17, 1235-1243.
Link
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36 |
“Residual counter ions can stabilise a large protein complex in the gas phase” Joanna Freeke, Carol V. Robinson, Brandon T. Ruotolo
Int. J. Mass Spectrom. (2010), 298, 91-98
Link
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35 |
“A Monte Carlo Approach for Assessing the Specificity of Protein Oligomers Observed in Nano-electrospray Mass Spectra” Laura A. Lane, Brandon T. Ruotolo, Carol V. Robinson, Giorgio Favrin, Justin L. P. Benesch
Int. J. Mass Spectrom. (2009), 283, 169-177.
Link
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34 |
“Gas-phase Unfolding and Disassembly Reveals Stability Differences in Ligand-bound Multi-protein Complexes” Suk-Joon Hyung, Carol V. Robinson, Brandon T. Ruotolo
Chem. Biol. (2009), 16, 382-390.
Link
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33 |
“Coupling Microdroplet Microreactors with Mass Spectrometry: Reading the Contents of Single Droplets On-line” Luis M. Fidalgo, Graeme Whyte, Brandon T. Ruotolo, Justin L. P. Benesch, Florian Stengel, Chris Abell, Carol V. Robinson, Wilhelm T.S. Huck
Agnew. Chem. Int. Ed. (2009), 48, 3665-3668.
Link
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32 |
“Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease” Summer L. Bernstein, Nichlas F. Dupuis, Noel Lazo, Thomas Wyttenbach, Margaret M. Condron, Gal Bitan, David B. Teplow, Joan-Emma Shea, Brandon T. Ruotolo, Carol V. Robinson, Michael T. Bowers
Nature Chem. (2009), 1, 326-331.
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31 |
“Quadrupole Time-of-Flight Mass Spectrometer Modified for Higher-Energy Dissociation Reduces Protein Assemblies to Peptide Fragments” Justin L. P. Benesch, Brandon T. Ruotolo, Frank Sobott, Jason Wildgoose, Anthony Gilbert, Robert H. Bateman, Carol V. Robinson
Anal. Chem. (2009), 81, 1270-1274
Link
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30 |
“Ion Mobility-Mass Spectrometry Analysis of Large Protein-Protein Complexes” Brandon T. Ruotolo, Justin L. P. Benesch, Alan M. Sandercock, Suk-Joon Hyung, Carol V. Robinson
Nature Prot. (2008), 3, 139-1152.
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29 |
“Subunit architecture of intact protein complexes from mass spectrometry and homology modeling” Thomas Taverner, Helena Hernández, Michal Sharon, Brandon T. Ruotolo, Damien Davos, Robert Russell, Carol V. Robinson
Acc. Chem. Res. (2008), 41, 617-627.
Link
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28 |
“Ion Mobility-Mass Spectrometry Reveals Long-lived, Unfolded Intermediates in the Dissociation of Protein Complexes” Brandon T. Ruotolo, Suk-Joon Hyung, Paula M. Robinson, Kevin Giles, Robert H. Bateman, Carol V. Robinson
Agnew. Chem. Int. Ed. (2007) 46, 8001-8004.
Link
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27 |
“Protein Complexes in the Gas Phase: Technology for Structural Genomics and Proteomics” Justin L. P. Benesch, Brandon T. Ruotolo, Douglas A. Simmons, Carol V. Robinson
Chem. Rev. (2007) 107, 3544-3567.
Link
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26 |
“Aspects of Native Protein Structure are Retained in Vacuum” Brandon T. Ruotolo and Carol V. Robinson
Curr. Opin. Chem. Biol. (2006) 10, 402-408.
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25 |
“Structural Basis for the Inhibition of Activin Signaling by Follistatin” Adrian E. Harrington, Samantha Morris-Triggs, Brandon T. Ruotolo, Carol V. Robinson, Shin-ichi Ohnuma, Marko Hyvönen
EMBO J. (2006) 25, 1035-1045.
Link
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24 |
"Accurate Mass Measurements Defines the Protein Composition of Intact Ribosomes and 30S Ribosomal subunits” Adam R. McKay, Brandon T. Ruotolo, Carol V. Robinson
J. Am. Chem. Soc. (2006) 128, 11433-11442.
Link
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23 |
“Tandem Mass Spectrometry Reveals the Quaternary Organization Of Macromolecular Assemblies” Justin L.P. Benesch, J. Andrew Aquilina, Brandon T. Ruotolo, Frank Sobott, Carol V. Robinson
Chem. Biol. (2006) 13, 597-605.
Link
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22 |
"“Evidence for Macromolecular Protein Rings in the Absence of Bulk Water” Brandon T. Ruotolo, Kevin Giles, Iain Campuzano, Alan M. Sandercock, Robert H. Bateman, Carol V. Robinson
Science (2005) 310, 1658-1661.
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21 |
“Characterization of Symmetrical Complexes of Nerve Growth Factor and the Ectodomain of the Pan-neurotrophin Receptor, p75.” Jukka P. Aurikko, Brandon T. Ruotolo, J. G. Grossmann, M. Moncrieffe, Elaine Stephens, V-M. Leppanen, Carol V. Robinson, M. Saarma, R. A. Bradshaw, Tom L. Blundell
J. Biol. Chem. (2005) 280, 33453-33460.
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20 |
“The Structure of Gas-Phase Bradykinin Fragment 1-5 (RPPGF) Ions: An Ion Mobility Spectrometry and H/D Exchange Ion-Molecule Reaction Chemistry Study” Holly A. Sawyer, Joseph T. Marini, Earle G. Stone, Brandon T. Ruotolo, Kent J. Gillig, David H. Russell
J. Am. Soc. Mass Spectrom. (2005) 16, 893-905.
Link
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19 |
“Ion Mobility-Mass Spectrometry: A New Paradigm for Proteomics” John A. McLean, Brandon T. Ruotolo, Kent J. Gillig, David H. Russell Int.
J. Mass Spectrom. (2005) 240, 301-315.
Link
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18 |
“The Influence and Utility of Varying Field Strength for the Separation of Tryptic Peptides by Ion Mobility-Mass Spectrometry” Brandon T. Ruotolo, John A. McLean, Kent J. Gillig, David H. Russell
J. Am. Soc. Mass Spectrom. (2005) 16, 158-165.
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17 |
“Analysis of Phosphorylated Peptides by Ion Mobility-Mass Spectrometry” Brandon T. Ruotolo, Kent J. Gillig, Amina S. Woods, Thomas F. Egan, Michael V. Ugerov, J. Albert Schultz, David H. Russell
Anal. Chem. (2004) 76, 6727-6733.
Link
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16 |
“Ion Mobility-Mass Spectrometry Applied to Cyclic Peptide Analysis: Conformational Preferences of Gramicidin S and Linear Analogues in the Gas Phase” Brandon T. Ruotolo, Colby C. Tate, David H. Russell
J. Am. Soc. Mass Spectrom. (2004) 15, 870-878.
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15 |
“Gas-Phase Conformations of Proteolytically-Derived Protein Fragments: The Influence of Solvent on Peptide Conformation” Brandon T. Ruotolo and David H. Russell
J. Phys. Chem. B. (2004) 108, 15321-15331.
Link
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14 |
“Resolution Equations for High-Field Ion Mobility Spectrometry” Guido F. Verbeck, Brandon T. Ruotolo, Kent J. Gillig, David H. Russell
J. Am. Soc. Mass Spectrom. (2004) 15, 1320-1324.
Link
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13 |
“Peak Capacity of Ion Mobility Separation. Utility of Altering Drift Gas Polarizability for Tryptic Peptide Separation” Brandon T. Ruotolo, John A. McLean, Kent J. Gillig, David H. Russell
J. Mass Spectrom. (2004) 39, 361-367.
Link
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12 |
“An Electrostatic Ion Guide for Ion Mobility-Mass Spectrometry” Kent J. Gillig, Brandon T. Ruotolo, Earle G. Stone, David H. Russell
Int. J. Mass Spectrom. (2004) 239, 43-49.
Link
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11 |
“Peak Capacity of Ion Mobility Separation. Separation of Peptides in Helium” Brandon T. Ruotolo, Kent J. Gillig, Earle G. Stone, David H. Russell
J. Chrom. B. (2002) 782, 385-392.
Link
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10 |
“A Fundamental Introduction to Ion Mobility Mass Spectrometry Applied to the Analysis of Biomolecules” Guido F. Verbeck, Brandon T. Ruotolo, Holly A. Sawyer, Kent J. Gillig, David H. Russell
J. Biomolecular Tech. (2002) 13(2), 56-61.
Link
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9 |
“Oligonucleotide analysis with MALDI-ion-mobility-TOFMS” John M. Koomen, Brandon T. Ruotolo, Kent J. Gillig, John A. McLean, David H. Russell, Mijeong Kang, Kim R. Dunbar, Katrin Fuhrer, Marc Gonin, J. Albert Schultz.
Anal. Bioanal. Chem. (2002), 373(7), 612-617.
Link
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8 |
“Distinguishing between Phosphorylated and Non-phosphorylated Peptides by Ion Mobility-Mass Spectrometry” Brandon T. Ruotolo, Guido F. Verbeck IV, Lisa M. Thompson, Amina S. Woods, Kent J. Gillig, David H. Russell J. Proteome Res. (2002), 1(4), 303-306.
Link
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7 |
“Observation of Conserved Solution-Phase Secondary Structure in Gas-Phase Tryptic Peptides“ Brandon T. Ruotolo, Guido F. Verbeck IV, Lisa M. Thompson, Kent J. Gillig, David H. Russell
J. Am. Chem. Soc. (2002) 124(16), 4214-4215.
Link
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6 |
“A Study of Peptide-Peptide Interactions Using MALDI Ion Mobility o-TOF and ESI Mass Spectrometry” Amina S. Woods, John M. Koomen, Brandon T. Ruotolo, Kent J. Gillig, David H. Russell, Katrin Fuhrer, Marc Gonin, Thomas F. Egan, and Albert J. Schultz
J. Am. Soc. Mass Spectrom. (2002) 13(2), 166-169.
Link
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5 |
“Analysis of Protein Mixtures by MALDI-Ion Mobility-Orthogonal Time-of-Flight Mass Spectrometry” Brandon T. Ruotolo, Kent J. Gillig, Earle G. Stone, David H. Russell, Katrin Fuhrer, Marc Gonin, and Albert J. Schultz
Int. J. Mass Specrtrom. (2002), 219 (1), 253-267.
Link
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4 |
“Optimization of a MALDI-IM-SID-o-TOF Mass Spectrometer: Simultaneous Acquisition of Drift Time-Resolved MS1 and MS2 Spectra” Earle G. Stone, Kent J. Gillig, Brandon T. Ruotolo, David H. Russell
Int. J. Mass Specrtrom. (2001) 212 (1-3), 519-533.
Link
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3 |
“MALDI-Ion Mobility-Surface Induced Dissociation-Time-of-Flight mass spectral analysis of "in solution" digested proteins” Earle G. Stone, Kent J. Gillig, Brandon T. Ruotolo, Katrin Fuhrer, Marc Gonin, Albert J. Schultz, and David H. Russell
Anal. Chem. (2001) 73 (10), 2233-2238.
Link
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2 |
“Coupling High-Pressure MALDI with Ion Mobility-Orthogonal Time-of-Flight Mass Spectrometry” Kent J. Gillig, Brandon T. Ruotolo, Earle G. Stone, and David H. Russell, Katrin Fuhrer, Marc Gonin, and Albert J. Schultz
Anal. Chem. (2000) 72 (17), 3965-3971.
Link
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1 |
"Development of a sequential injection system in the capillary format for determinations of the IpaC protein” Dana M. Spence, Eric, D. Knoll, Brandon T. Ruotolo, Jens Bjerregaard
Anal. Chim. Acta (2000) 409 (1-2) 3-8.
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