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Intended Use
4D-MSPECT, developed at the University of Michigan
Medical Center in Ann Arbor, Michigan, is a
comprehensive
cardiac emission computed tomographic (ECT = SPECT + PET) image
quantification and display program for nuclear cardilogy
perfusion studies. 4D-MSPECT is designed to process
cardiac ECT studies and then display the images and quantitative
results in many user selectable formats. Effectively 4D-MSPECT provides
a single user friendly intuitive environment within which the operator,
technologist or physician, can efficiently process and review all
cardiac ECT perfusion studies.
4D-MSPECT provides customers with the ability to process, analyze and
display reconstructed cardiac tomographic studies of all types. The
application allows users to select from among a number of different
quantification and display routines through a standardized user
interface. The application allows users to select from among a number
of different single or multi-dimensional display(s) those that best fit
their needs. Among the several optional display screens are
side-by-side displays optimized for the review of uncorrected and
attenuation corrected cardiac images.
Quality assurance is an important part of
the operations of any
successful Nuclear Imaging laboratory. 4D-MSPECT provides several
options for verifying the quality of the input data and the processing
of that data. Raw data cines, surface, valve plane and polarmap QA of
all displayed studies are all provided and available both during
processing and subsequently during image interpretation. Whether
technologist or physician, these options are never more than a mouse
click or two away during any phase of processing or review.
A Normals Database
Generator is an integrated feature of 4D-MSPECT that
provides the individual user with a set of tools for generating site,
patient population or protocol specific normal data files. Site
specific Normals Databases are integrated seamlessly into the
application for research or daily clinical use. This is a user friendly
sophisticated module that provides individual subject and population
statistics and the ability to review and edit the included studies
(n=20 to 256) at the users convenience. Included in 4D-MSPECT is a
validated normal databases for the dual isotope rest Tl-201 stress
Tc-99m-Cardiolite/Myoview protocol, two day and one day
Tc-99m-Cardiolite/Myoview protocols.
4D-MSPECT is marketed by Siemens (ESOFT), Philips(Pegasys), and GE
(Xeleris). On each these platform, 4D-MSPECT is fully integrated
into vendors’clinical user interface and interfaces directly with the
vendor’s patient database. 4D-MSPECT automatically sorts the individual
image files for those that are pertinent to the application without the
need for tedious file sorting and user specified file selection. Thus,
the operator only needs to select the patients of interest, including
all of each patients files, without worrying about the selection of
only the appropriate files readable by the application. The individual
site can customize the application to recognize files specified by site
specific naming conventions. Display formats specific to the studies
selected are automatically generated and displayed. Several possible
display formats are selectable from pulldown menus within
4D-MSPECT. If the operator wants additional display options
for special situations, these may be easily specified, formatted and
saved with a few button clicks.
You
can use
the 4D-MSPECT application to do the following:
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Process and display cardiac
ECT and
gated ECT perfusion studies of all types.
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Process and display gated blood pool SPECT
studies.
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Calculate ventricular volumes and the
ejection fraction (EF) from gated ECT perfusion and blood pool
SPECT data sets.
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Generate and display 2D, 3D and polar
map images for independent or comparative review.
-
Compare perfusion polar maps to supplied
gender matched Tc-99m labelled tracers, Tl-201 or site specific normal
files to determine quantify extent, severity and reversibility of
perfusion defects.
-
Compare polar maps of regional ventricular
function (ie. wall motion and thickening) from gated perfusion or blood
pool studies to protocol specific normals files.
-
Export the estimated and user input
patient information (e.g. functional and perfusion data, patient
history, diagnostic impressions,..) in either report format, data
format or screen capture format to other 3rd party
applications (e.g. spreadsheets, HTML files, SQL databases).
4D-MSPECT Objectives
The objectives of 4D-MSPECT
are:
- To provide a single application for the
complete multi-dimensional analysis and display of cardiac ECT
images.
- To provide extensive quantitative analyses
of reconstructed cardiac ECT studies.
- To provide a fully automated customizable
tool for processing/analyzing and displaying reconstructed cardiac ECT
studies.
- To provide processing, analysis and display
tools for both ungated and ECG gated cardiac ECT studies.
- To provide processing, analysis and display
tools for both uncorrected and attenuation corrected cardiac ECT
studies.
- To provide convenient tools for generating
and integrating site specific normal data files.
Input Data Types
- Gated and ungated short-axis image files.
- Gated and ungated emission projection data
files.
- Any matrix size up to 256x256, up to 16 ECG
intervals, and voxel dimensions between 3.5mm and 7.2mm
- Uncorrected and attenuation
corrected cardiac images.
- Supports any radiopharmaceutical used for
myocardial perfusion tomography.
- Support for 180 and 360 degree
reconstruction arcs.
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