Biosensor

Quantitative detection of low concentration biomarker in physiological system is important for fundamental research to clinical applications. Among ultra-sensitive detection methods, Enzyme-linked immunosorbent assay (ELISA) has been extensively using in research and clinical laboratories. However, standard ELISA technique experiences from a few major drawbacks. The first flaw is long testing time. It usually takes 3-6 hours plus overnight pre-coating to complete the whole assay process. Secondly, a flaw is large sample consumption. Traditional, ELISA requires about 50-100 µL per well samples, hence a large amount of reagents, which adds significant costs. Lastly, a flaw is inadequate detection limit. At present, I am leading a research and development of next generation ELISA well-plate which could furnish faster, more sensitive, and less cost than currently available traditional well-plate in the market.